Evidence map›Paper›PMID 27892768›Full record

ArticleTranscription2017

TFEB and TFE3: The art of multi-tasking under stress conditions.

José A Martina, Rosa Puertollano

Open access · bronzeAbstract read
In one paragraph

Article in Transcription, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
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  7. Article
  8. Role of TFEB in Diseases Associated with Lysosomal Dysfunction.Advances in experimental medicine and biology · 2023
    Article
  9. Article
  10. Review
  11. Article
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  19. Article
  20. Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

José A Martinaa Cell Biology and Physiology Center , National Heart, Lung, and Blood Institute, National Institutes of Health , Bethesda , MD , USA.
Rosa Puertollanoa Cell Biology and Physiology Center , National Heart, Lung, and Blood Institute, National Institutes of Health , Bethesda , MD , USA.
National Institutes of Health · US

Funding

Lysosome biogenesis and homeostasisZIAHL006151 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI PUERTOLLANO, ROSA · 2012 to 2025
$15.0M
6 · The paper itself

Abstract

Cellular adaptation response to a myriad of stressors is key for survival. The lysosomal/autophagy pathway is inextricably connected to the stress response regulation. Two transcription factors, TFEB and TFE3, have recently emerged as master regulators of this degradative pathway. Their function modulating different cellular pathways will be discussed.

Indexed as

Stress, PhysiologicalAutophagyBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsGene Expression RegulationHumansLysosomesSignal TransductionBasic Helix-Loop-Helix Leucine Zipper Transcription FactorsTFE3 protein, humanTFEB protein, humanautophagylysosomesstressTFE3TFEB

Identifiers

PMID27892768
PMCPMC5279710
OpenAlexW2559637918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.