ArticlePlant biotechnology journal2017
The rice OsNAC6 transcription factor orchestrates multiple molecular mechanisms involving root structural adaptions and nicotianamine biosynthesis for drought tolerance.
Article in Plant biotechnology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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77 citing papers in PubMed.
- Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate-resilient apple breeding.Journal of integrative plant biology · 2026Article
- Molecular and Genetic Regulation of Crop Root System Architecture in Drought Resilience.Plants (Basel, Switzerland) · 2026Review
- Cloning and functional analysis of the HaNAC11 transcription factor in Haloxylon ammodendron.BMC plant biology · 2026Article
- From paddy soil to dining table: biological biofortification of rice with zinc.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Molecular Mechanisms and Experimental Strategies for Understanding Plant Drought Response.Plants (Basel, Switzerland) · 2026Review
- Integrative physiological and transcriptome analysis ofFrontiers in plant science · 2026Article
- Superior haplotypes of genes associated with higher grain yield under reproductive stage drought stress in rice.Journal of experimental botany · 2025Article
- Precipitation legacy effects on soil microbiota facilitate adaptive drought responses in plants.Nature microbiology · 2025Article
- Synergistic Response Mechanisms in Rice Seedlings Exposed to Brown Planthopper Infestation and High-Temperature Stress.Plants (Basel, Switzerland) · 2025Article
- NAC transcription factors are key regulators of Brassinolide-Enhanced drought tolerance in Camellia oil tree.BMC plant biology · 2025Article
- The ETHYLENE RESPONSE FACTOR6-GRETCHEN HAGEN3.5 module regulates rooting and heat tolerance in Dimocarpus longan.Plant physiology · 2025Article
- Review
- LOGOWheat: deep learning-based prediction of regulatory effects for noncoding variants in wheats.Briefings in bioinformatics · 2024Article
- Rice Promoter Editing: An Efficient Genetic Improvement Strategy.Rice (New York, N.Y.) · 2024Review
- A Case Study from the Overexpression of OsTZF5, Encoding a CCCH Tandem Zinc Finger Protein, in Rice Plants Across Nineteen Yield Trials.Rice (New York, N.Y.) · 2024Article
- Tea-Derived Polyphenols Enhance Drought Resistance of Tea Plants (International journal of molecular sciences · 2024Article
- OsNAC120 balances plant growth and drought tolerance by integrating GA and ABA signaling in rice.Plant communications · 2024Article
- Zeocin-induced DNA damage response in barley and its dependence on ATR.Scientific reports · 2024Article
- RtNAC055 promotes drought tolerance via a stomatal closure pathway linked to methyl jasmonate/hydrogen peroxide signaling inHorticulture research · 2024Article
- Ethylene Modulates Rice Root Plasticity under Abiotic Stresses.Plants (Basel, Switzerland) · 2024Review
17 more citing papers are in PubMed but not listed here.
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10 authors.
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Abstract
Drought has a serious impact on agriculture worldwide. A plant's ability to adapt to rhizosphere drought stress requires reprogramming of root growth and development. Although physiological studies have documented the root adaption for tolerance to the drought stress, underlying molecular mechanisms is still incomplete, which is essential for crop engineering. Here, we identified OsNAC6-mediated root structural adaptations, including increased root number and root diameter, which enhanced drought tolerance. Multiyear drought field tests demonstrated that the grain yield of OsNAC6 root-specific overexpressing transgenic rice lines was less affected by drought stress than were nontransgenic controls. Genome-wide analyses of loss- and gain-of-function mutants revealed that OsNAC6 up-regulates the expression of direct target genes involved in membrane modification, nicotianamine (NA) biosynthesis, glutathione relocation, 3'-phophoadenosine 5'-phosphosulphate accumulation and glycosylation, which represent multiple drought tolerance pathways. Moreover, overexpression of NICOTIANAMINE SYNTHASE genes, direct targets of OsNAC6, promoted the accumulation of the metal chelator NA and, consequently, drought tolerance. Collectively, OsNAC6 orchestrates novel molecular drought tolerance mechanisms and has potential for the biotechnological development of high-yielding crops under water-limiting conditions.
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