Evidence map›Paper›PMID 27891482›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

Treatment Emergent Agranulocytosis with Skin and Gingival Lesions in a Chronic Lymphocytic Leukemia Patient: A Case Report.

Ramesh Amirisetty, Varun Zade, Meenakshi Boddun, Rolly Gupta, Micky Kumari, Hema Suryawanshi

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ramesh AmirisettyProfessor, Department of Periodontology, Chhattisgarh Dental College and Research Institute , Rajnandgaon, Chhattisgarh, India .
Varun ZadeLecturer, Department of Periodontology, Chhattisgarh Dental College and Research Institute , Rajnandgaon, Chhattisgarh, India .
Meenakshi BoddunLecturer, Department of Periodontology, Chhattisgarh Dental College and Research Institute , Rajnandgaon, Chhattisgarh, India .
Rolly GuptaReader, Department of Oral Pathology and Microbiology, Chhattisgarh Dental College and Research Institute , Rajnandgaon, Chhattisgarh, India .
Micky KumariPostgraduate Student, Department of Periodontology, Chhattisgarh Dental College and Research Institute , Rajnandgaon, Chhattisgarh, India .
Hema SuryawanshiProfessor and Head, Department of Oral Pathology and Microbiology, Chhattisgarh Dental College and Research Institute , Rajnandgaon, Chhattisgarh, India .
Chhattisgarh Dental College & Research Institute · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic Lymphocytic Leukaemia (CLL) is a monoclonal lymphoid malignancy characterized by progressive accumulation of small, mature but functionally incompetent neoplastic lymphocytes in the peripheral blood, bone marrow and lymphoid organs. Patients present a variable course and may not require early intervention unlike other malignancies. Patients with rapidly deteriorating blood counts, and organomegaly need treatment. Alkylating agent live Bendamustine combined with Rituximab, anti-CD 20 monoclonal antibody have shown promising results in such patients. Anaemia, neutropenia and thrombocytopenia have been reported as treatment emergent events with this combination therapy. Neutrophils are the major innate defense and their depletion can result in a wide range of opportunistic infections. This case report discusess the oral and dermal lesions which emerged with the Rituximab and Bendamustine combination therapy in a patient with CLL and their management.

Indexed as

BendamustineGingival necrosisNeutropeniaRituximab

Identifiers

PMID27891482
PMCPMC5121820
OpenAlexW2558160214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.