ArticleJournal of clinical and diagnostic research : JCDR2016
High Seroprevalence of Dengue Virus Infection in Blood Donors From Delhi: A Single Centre Study.
Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Prevalence of Chikungunya, Dengue and Zika viruses in blood donors: a systematic literature review and meta-analysis.Blood transfusion = Trasfusione del sangue · 2022Pooled it
- Dengue infection in India: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2018Pooled it
- Dengue Virus Biosafety: An Analysis of Evidence, Global Inconsistencies, and Risk Gaps.Applied biosafety : journal of the American Biological Safety Association · 2025Review
- Scrub typhus in Indonesia: A cross-sectional analysis of archived fever studies samples.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2024Article
- High prevalence of dengue, Zika, and chikungunya viruses in blood donors during a dengue outbreak and an endemic period in Colombia.Frontiers in medicine · 2024Article
- Screening for arboviruses in healthy blood donors: Experience from Karachi, Pakistan.Virologica Sinica · 2022Article
- Seroprevalence and incidence of primary dengue infections among children in a rural region of Maharashtra, Western India.BMC infectious diseases · 2019Article
- Dengue and chikungunya seroprevalence among Qatari nationals and immigrants residing in Qatar.PloS one · 2019Article
- Dengue seroprevalence among asymptomatic blood donors during an epidemic outbreak in Central-West Brazil.PloS one · 2019Article
- Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review.PLoS neglected tropical diseases · 2018Article
- Low frequency of asymptomatic dengue virus-infected donors in blood donor centers during the largest dengue outbreak in Taiwan.PloS one · 2018Article
- Outcome of Adult Malarial Co-infections in Eastern India.Journal of global infectious diseasesArticle
- Dengue seropositivity among blood donors in a tertiary hospital in Kerala, Southern India.Annals of African medicineArticle
- Prevalence of dengue NS1 antigenemia among healthy blood donors in a tertiary care hospital in Southern India.Asian journal of transfusion scienceArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe risk of transfusion transmitted dengue has been increasingly recognized. Blood donors in an endemic area like Delhi may serve as a potential vehicle for transmission of the infection. Moreover, prevalence of infection in them would be representative of the true picture of dengue in a population.
aimTo determine the prevalence of dengue virus infection in blood donors in a tertiary care centre. MATERIALS AND
methodsA total of 200 blood donors were recruited in the study after obtaining informed consent in the Institute of Liver and Biliary Sciences, New Delhi in July and August 2012. Data regarding clinical and demographic characteristics was collected using a preformed questionnaire. Blood samples obtained were subjected to anti-dengue IgM and IgG ELISA as well as semi-nested Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) for dengue RNA.
resultsOf the study subjects, most were men (97%) with a median age of 28 years (range 19-51 years). Anti-dengue IgG was positive in 116 cases (58%) while IgM was seen in 27cases (13.5%). Of them, in 25 (12.5%) cases both IgG and IgM were positive, while only two (1%) cases tested positive for IgM alone. None of the blood donors were found to be viremic on screening using Nested RT-PCR. A clear increase of IgG seroprevalence with age was evident. No difference in the seroprevalence rates in urban vs. rural areas was seen.
conclusionHigh seroprevalence of dengue infection was seen in healthy asymptomatic blood donors. Though evidence of acute infection was found in some, none were found to be viremic. Larger studies are required to quantify the risk and provide strong evidence for policies to be made.
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