ArticleBMC hematology2016
Prevalence of transfusion transmissible infections in blood donors of Pakistan.
Article in BMC hematology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Pooled it
- Seroprevalence of hepatitis c virus infection among blood donors in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2021Pooled it
- Prevalence of transfusion-transmissible infections and associated sociodemographic risk factors among blood donors at a tertiary care hospital in Lahore, Pakistan.BMC infectious diseases · 2026Article
- Seroprevalence of Hepatitis-E infection in healthy blood donors in an endemic country.Pakistan journal of medical sciences · 2026Article
- Seroprevalence and Risk Factors of STIs among Rejected Blood Donors at the National Blood Transfusion Service in Angola.AIDS and behavior · 2025Article
- Prevalence and Risk Factors of Transfusion-Transmissible Infections Among Voluntary Blood Donors in North Shoa, Amhara Region, Ethiopia: A Cross-Sectional Study.Health science reports · 2025Article
- Seroprevalence of HIV, HBV, HCV and Syphilis among blood donors in a Nigerian tertiary medical centre.BMC infectious diseases · 2025Article
- Article
- Assessment of prevalence and risk factors associated with Hepatitis B virus infection among blood donors in Mogadishu Somalia.BMC public health · 2024Article
- Transfusion transmitted infections among blood donors of Kamenge Teaching Hospital blood bank in Burundi.African health sciences · 2024Article
- Article
- Genetic diversity of the human immunodeficiency virus of type 1 in Gabonese transfusional settings.BMC infectious diseases · 2023Article
- Frequency of transfusion transmissible infections among blood donors of Rawalpindi District, Pakistan.African health sciences · 2022Observational
- Article
- The Prevalence of Transfusion Transmitted Infections among Blood Donors in Pakistan: A Retrospective Study.Oman medical journal · 2022Article
- Seroprevalence of the Serological Markers of Transfusion-Transmissible Infections among Volunteer Blood Donors of Kosti Obstetrics and Gynecology Hospital.Medicines (Basel, Switzerland) · 2021Article
- Article
- Seroprevalence of Transfusion-Transmitted Infections among Voluntary and Replacement Blood Donors at the Peshawar Regional Blood Centre, Khyber Pakhtunkhwa, Pakistan.Journal of laboratory physicians · 2021Article
- Prevalence and trends of transfusion transmissible infections among blood donors in the State of Qatar, 2013-2017.BMC infectious diseases · 2020Article
- A Systematic Review of Transfusion-Transmissible Infections Among Blood Donors and Associated Safety Challenges in Pakistan.Journal of blood medicine · 2020Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransfusion-transmitted infections threaten the safety of patients requiring blood transfusion, which in turn imposes serious challenges for the availability of safe blood products that are still affordable in health care systems with limited resources. The aim of the study was to determine the prevalence of transfusion-transmitted infections in blood donors and to evaluate the demographic characteristics of reactive and non-reactive blood donors.
methodsA prospective cohort study was conducted at our institute in Karachi, Pakistan. Donors were required to fill a detailed questionnaire and were screened for Hepatitis B, Hepatitis C, Human immunodeficiency viruses, Syphilis and Malaria by ELISA and thick film (malaria).
resultsOf the 16,602 blood donors, 16,557 were males and 45 females (mean age 28.6 ± 2). Nine hundred and seventy three (5.8%) donations were reactive in any screening assay, with 58 (0.35%) donations reacting in more than one assay. The prevalence of Hepatitis B, Hepatitis C, Human immunodeficiency viruses, Syphilis and Malaria was found to be 1.84, 1.7, 0.04, 2.1 and 0.07% respectively. Characteristics among the infections were evaluated and it was found that unmarried donors had a higher chance to be infected by Hepatitis B virus and Syphilis as compared to the other infections. On the other hand, construction workers and married donors were at more risk to be infected by Syphilis rather than the other infections. In case of co-infections, personnel with different occupations and marital status were infected by more than one pathogen.
conclusionA substantial percentage of the blood donor's harbored transfusion-transmitted infections. Prevention of TTIs should be the main goal right now. There is a need for stringent selection of blood donors with the emphasis on getting voluntary donations and comprehensive screening of donor's blood for TTIs using standard methods to ensure the safety of blood recipient.
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