Evidence map›Paper›PMID 27891173›Full record

ArticleWorld journal of emergency surgery : WJES2016

Laparoscopic cholecystectomy for acute calculous cholecystitis: a retrospective study assessing risk factors for conversion and complications.

Petra Maria Terho, Ari Kalevi Leppäniemi, Panu Juhani Mentula

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03477253 (Laparoscopic Cholecystectomy for Management of Acute Calculous Cholecystitis Within Versus After 3 Days of Disease Onset), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03477253 nacompletednot on this mapstarted 2017, after this paper: background citation

Laparoscopic Cholecystectomy for Management of Acute Calculous Cholecystitis Within Versus After 3 Days of Disease Onset

TypeinterventionalSponsorAssiut UniversityRan2017 to 2020Enrolled62ConditionsAcute Calculous CholecystitisArmsLaparoscopic cholecystectomy
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Petra Maria TerhoInstitute of Clinical Medicine, Faculty of Medicine, University of Helsinki, Haartmaninkatu 8, 00014 Helsinki, Finland.
Ari Kalevi LeppäniemiDepartment of Abdominal Surgery, Helsinki University Central Hospital, P.O.Box 340, 00029 HUS Helsinki, Finland.
Panu Juhani MentulaDepartment of Abdominal Surgery, Helsinki University Central Hospital, P.O.Box 340, 00029 HUS Helsinki, Finland.
Helsinki University Hospital · FIUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of the study was to identify risk factors for conversion of laparoscopic cholecystectomy and risk factors for postoperative complications in acute calculous cholecystitis. The most common complications arising from cholecystectomy were also to be identified.

methodsA total of 499 consecutive patients, who had undergone emergent cholecystectomy with diagnosis of cholecystitis in Meilahti Hospital in 2013-2014, were identified from the hospital database. Of the identified patients, 400 had acute calculous cholecystitis of which 27 patients with surgery initiated as open cholecystectomy were excluded, resulting in 373 patients for the final analysis. The Clavien-Dindo classification of surgical complications was used.

resultsLaparoscopic cholecystectomy was initiated in 373 patients of which 84 (22.5%) were converted to open surgery. Multivariate logistic regression identified C-reactive protein (CRP) over 150 mg/l, age over 65 years, diabetes, gangrene of the gallbladder and an abscess as risk factors for conversion. Complications were experienced by 67 (18.0%) patients. Multivariate logistic regression identified age over 65 years, male gender, impaired renal function and conversion as risk factors for complications.

conclusionsAdvanced cholecystitis with high CRP, gangrene or an abscess increase the risk of conversion. The risk of postoperative complications is higher after conversion. Early identification and treatment of acute calculous cholecystitis might reduce the number of patients with advanced cholecystitis and thus improve outcomes.

Indexed as

Cholecystectomy, LaparoscopicCholecystitis, AcutePostoperative ComplicationsAdultAgedAge FactorsCholelithiasisEarly DiagnosisFemaleFinlandHumansKidney Function TestsLogistic ModelsMaleMiddle AgedOutcome and Process Assessment, Health CareAcute cholecystitisConversionLaparoscopic cholecystectomyOpen cholecystectomy

Identifiers

PMID27891173
PMCPMC5112701
OpenAlexW2554834064

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.