Evidence map›Paper›PMID 27891160›Full record

ArticleAIDS research and therapy2016

HIV sero-discordance among married HIV patients initiating anti-retroviral therapy in northern Vietnam.

Vu Van Tam, Do Duy Cuong, Tobias Alfven, Ho Dang Phuc, Nguyen Thi Kim Chuc, Nguyen Phuong Hoa, Vinod Diwan, Mattias Larsson

Open access · goldAbstract read
In one paragraph

Article in AIDS research and therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Vu Van TamDivision of Global Health, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden.
Do Duy CuongDivision of Global Health, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden.
Tobias AlfvenDivision of Global Health, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden.
Ho Dang PhucDepartment of Probability and Mathematical Statistics, Institute of Mathematics, Ha Noi, Vietnam.
Nguyen Thi Kim ChucHealth System Research Project, Ha Noi Medical University, Ha Noi, Vietnam.
Nguyen Phuong HoaHealth System Research Project, Ha Noi Medical University, Ha Noi, Vietnam.
Vinod DiwanDivision of Global Health, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden.
Mattias LarssonDivision of Global Health, Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden ; Oxford University Clinical Research Unit, Ha Noi, Vietnam.ORCID 0000-0002-0514-7445
Karolinska Institutet · SEHanoi Medical University · VNInstitute of Mathematics · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn many countries in Asia, the HIV epidemic is in a concentrated phase, with high prevalence in certain risk groups, such as men who inject drugs. There is also a rapid increase of HIV among women. The latter might be due to high levels of sero-discordant couples and increasing transmission from male to female partners over time.

methodsAll adult married patients initiating antiretroviral treatment at four out-patient clinics in Quang Ninh province in north-eastern Vietnam between 2007 and 2009 were asked to participate in the study. Clinical information was extracted from patients' records, and a structured questionnaire was used to collect social, demographic and economic data.

resultsTwo hundred eighty-eight married patients for whom information on the HIV status of their spouse was available were included in the study. Overall, the sero-discordance rate was 58%. The sero-discordance rate was significantly higher among married males, 71% had spouses not infected, than married females, of whom 18% had spouses not infected. Other factors associated with a high rate of sero-discordance were injection drug use (IDU) history, tuberculosis (TB) history and the availability of voluntary counselling and testing (VCT) in residential locations. High sero-concordance was associated with college/university education.

conclusionThe sero-discordance was significantly higher among married males than married females. Other factors also related to high sero-discordance were history of IDU, history of TB and the availability of VCT in residential locations. In contrast, college/university education and female sex were significantly related to low sero-discordance. To contain the increasing HIV prevalence among women, measures should be taken to prevent transmission among sero-discordant couples.

Indexed as

AdolescentAdultAnti-Retroviral AgentsCD4 Lymphocyte CountFamily CharacteristicsFemaleHIV InfectionsHumansMaleMarriageMiddle AgedOutpatientsPrevalenceRisk FactorsSexual PartnersSocioeconomic FactorsAnti-Retroviral AgentsARTGenderHIVLate presentationSero-discordanceVietnam

Identifiers

PMID27891160
PMCPMC5109648
OpenAlexW2549917970

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.