ReviewFrontiers in neurology2016
Deep Brain Stimulation for Tourette's Syndrome: The Case for Targeting the Thalamic Centromedian-Parafascicular Complex.
Review in Frontiers in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 37 citations in OpenAlex.
- Thalamic nuclei volume changes associated with cognitive and motor manifestations of Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Identifying texture features from structural magnetic resonance imaging scans associated with Tourette's syndrome using machine learning.Journal of medical imaging (Bellingham, Wash.) · 2025Article
- Deep brain stimulation alleviates tics in Tourette syndrome via striatal dopamine transmission.Brain : a journal of neurology · 2023Article
- The structural connectivity mapping of the intralaminar thalamic nuclei.Scientific reports · 2023Article
- Micropopulation mapping of the mouse parafascicular nucleus connections reveals diverse input-output motifs.Frontiers in neuroanatomy · 2023Article
- European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part IV: deep brain stimulation.European child & adolescent psychiatry · 2022Review
- An open-label prospective pilot trial of nucleus accumbens deep brain stimulation for children with autism spectrum disorder and severe, refractory self-injurious behavior: study protocol.Pilot and feasibility studies · 2022Article
- Successful Treatment of Psychiatric Symptoms after Traumatic Brain Injury Using Deep Brain Stimulation to the Anterior Limb of Internal Capsule-Nucleus Accumbens.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2020Article
- Clinical applications of neurochemical and electrophysiological measurements for closed-loop neurostimulation.Neurosurgical focus · 2020Article
- Deep brain stimulation for Tourette's syndrome.Translational neurodegeneration · 2020Review
- Case Report: Deep Brain Stimulation to the Ventral Internal Capsule/Ventral Striatum Induces Repeated Transient Episodes of Voltage-Dependent Tourette-Like Behaviors.Frontiers in human neuroscience · 2020Article
- Article
- Imaging the Centromedian Thalamic Nucleus Using Quantitative Susceptibility Mapping.Frontiers in human neuroscience · 2019Article
- On the neuronal circuitry mediating L-DOPA-induced dyskinesia.Journal of neural transmission (Vienna, Austria : 1996) · 2018Review
- Anatomy, Physiology, and Clinical Syndromes of the Basal Ganglia: A Brief Review.Seminars in pediatric neurology · 2018Review
- Review of the evidence for the management of co-morbid Tic disorders in children and adolescents with attention deficit hyperactivity disorder.World journal of clinical pediatrics · 2018Review
- Global network modulation during thalamic stimulation for Tourette syndrome.NeuroImage. Clinical · 2018Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tourette's syndrome (TS) is a neurologic condition characterized by both motor and phonic tics and is typically associated with psychiatric comorbidities, including obsessive-compulsive disorder/behavior and attention-deficit hyperactivity disorder, and can be psychologically and socially debilitating. It is considered a disorder of the cortico-striato-thalamo-cortical circuitry, as suggested by pathophysiology studies and therapeutic options. Among these, deep brain stimulation (DBS) of the centromedian-parafascicular nucleus (CM-Pf) of the thalamus is emerging as a valuable treatment modality for patients affected by severe, treatment-resistant TS. Here, we review the most recent experimental evidence for the pivotal role of CM-Pf in the pathophysiology of TS, discuss potential mechanisms of action that may mediate the effects of CM-Pf DBS in TS, and summarize its clinical efficacy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.