Evidence map›Paper›PMID 27891048›Full record

ArticleMagnetic resonance insights2016

Metabolic Signatures of Lung Cancer in Sputum and Exhaled Breath Condensate Detected by

Naseer Ahmed, Tedros Bezabeh, Omkar B Ijare, Renelle Myers, Reem Alomran, Michel Aliani, Zoann Nugent, Shantanu Banerji, Julian Kim, Gefei Qing and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Magnetic resonance insights, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
  6. Monitoring non-small cell lung cancer progression and treatment response through hyaluronic acid in sputum.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Early diagnosis and screening in lung cancer.American journal of cancer research · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Clinical Utility of Chromosomal Aneusomy in Individuals at High Risk of Lung Cancer.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2017
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Naseer AhmedCancerCare Manitoba, Winnipeg, Manitoba, Canada.; University of Manitoba, Winnipeg, Manitoba, Canada.
Tedros BezabehDepartment of Chemistry, University of Winnipeg, Winnipeg, Manitoba, Canada.; Current address: College of Natural and Applied Sciences, University of Guam, Guam, USA.
Omkar B IjareDepartment of Chemistry, University of Winnipeg, Winnipeg, Manitoba, Canada.
Renelle MyersDepartment of Respirology, Health Sciences Centre, University of Manitoba, Winnipeg, Manitoba, Canada.
Reem AlomranCancerCare Manitoba, Winnipeg, Manitoba, Canada.; University of Manitoba, Winnipeg, Manitoba, Canada.
Michel AlianiDepartment of Human Nutritional Sciences, University of Manitoba, Winnipeg, Canada.; St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, Canada.
Zoann NugentCancerCare Manitoba, Winnipeg, Manitoba, Canada.
Shantanu BanerjiCancerCare Manitoba, Winnipeg, Manitoba, Canada.; University of Manitoba, Winnipeg, Manitoba, Canada.
Julian KimCancerCare Manitoba, Winnipeg, Manitoba, Canada.; University of Manitoba, Winnipeg, Manitoba, Canada.
Gefei QingDepartment of Pathology, Health Sciences Centre, University of Manitoba, Winnipeg, Manitoba, Canada.
Zoheir BshoutyDepartment of Respirology, Health Sciences Centre, University of Manitoba, Winnipeg, Manitoba, Canada.
University of Manitoba · CACancerCare Manitoba · CAUniversity of Guam · GUUniversity of Winnipeg · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesLung cancer is one of the most lethal cancers. Currently, there are no biomarkers for early detection, monitoring treatment response, and detecting recurrent lung cancer. We undertook this study to determine if MATERIALS AND

methodsSputum and EBC samples were collected from 20 patients, comprising patients with pathologically confirmed non-small cell lung cancer (

resultsIn the EBC samples, median concentrations of propionate, ethanol, acetate, and acetone were higher in lung cancer patients compared to the patients with benign conditions. Median concentration of methanol was lower in lung cancer patients (0.028 mM) than in patients with benign conditions (0.067 mM;

conclusionAbsence of glucose in sputum and lower concentrations of methanol in EBC of lung cancer patients discerned by

Indexed as

breath condensatelung cancermagnetic resonance spectroscopysputum

Identifiers

PMID27891048
PMCPMC5117486
OpenAlexW2550721449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.