ReviewNeuroImage2018
Quantitative sodium MR imaging: A review of its evolving role in medicine.
Review in NeuroImage, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- Variability by region and method in human brain sodium concentrations estimated byScientific reports · 2023Pooled it
- Ultra-high-field sodium MRI as biomarker for tumor extent, grade and IDH mutation status in glioma patients.NeuroImage. Clinical · 2020Trial
- Time-Efficient Interleaved Spin Density-Weighted and Inversion RecoveryMagnetic resonance in medicine · 2026Article
- A Sub-Microsecond Switch Enabling SWIFTMagnetic resonance in medicine · 2026Article
- Multinuclear NMR and MRI Beyond Proton Imaging: Principles, Contrast Mechanisms, and Applications in Materials and Biomedicine.International journal of molecular sciences · 2026Review
- Signal-to-noise ratio comparison of k-space sampling schemes for sodium MRI of the brain at 3 T.Magma (New York, N.Y.) · 2026Article
- Article
- High spatial resolutionbioRxiv : the preprint server for biology · 2026Article
- Mapping Regional Brain Total Sodium Concentration Using Anatomically Guided Reconstruction of Dual-Echo Sodium-23 MRI: Moving toward Improved Accuracy and Precision.AJNR. American journal of neuroradiology · 2026Article
- Added Value of Sodium MR Imaging and Proton MR Spectroscopy to Conventional MR Imaging for a Better Characterization of the Ischemic Stroke: A Narrative Review.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Review
- Added value of sodium MRI in multiparametric MRI for WHO grade II astrocytoma surveillance during "watchful waiting": initial experience.Radiologie (Heidelberg, Germany) · 2025Article
- Quantitative abdominal sodium MRI combined with 32-channel proton pTx MRI at 7 Tesla in a large field-of-view.Magnetic resonance in medicine · 2025Article
- Super-resolution sodium MRI of human gliomas at 3T using physics-based generative artificial intelligence.Journal of neuro-oncology · 2025Article
- Polyacrylamide Gel Calibration Phantoms for Quantification in Sodium MRI.NMR in biomedicine · 2025Article
- Different sodium concentrations of noncancerous and cancerous prostate tissue seen on MRI using an external coil.Radiology advances · 2024Article
- Hardware and Software Setup for QuantitativeSensors (Basel, Switzerland) · 2024Article
- Resolution enhancement, noise suppression, and joint T2* decay estimation in dual-echo sodium-23 MR imaging using anatomically guided reconstruction.Magnetic resonance in medicine · 2024Article
- Mice and minipigs with compromised expression of the Alzheimer's disease geneBrain communications · 2024Article
- Radiosurgery-induced early changes in peritumoral tissue sodium concentration of brain metastases.PloS one · 2024Article
- Label-Free Chemically and Molecularly Selective Magnetic Resonance Imaging.Chemical & biomedical imaging · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Sodium magnetic resonance (MR) imaging in humans has promised metabolic information that can improve medical management in important diseases. This technology has yet to find a role in clinical practice, lagging proton MR imaging by decades. This review covers the literature that demonstrates that this delay is explained by initial challenges of low sensitivity at low magnetic fields and the limited performance of gradients and electronics available in the 1980s. These constraints were removed by the introduction of 3T and now ultrahigh (≥7T) magnetic field scanners with superior gradients and electronics for proton MR imaging. New projection pulse sequence designs have greatly improved sodium acquisition efficiency. The increased field strength has provided the expected increased sensitivity to achieve resolutions acceptable for metabolic interpretation even in small target tissues. Consistency of quantification of the sodium MR image to provide metabolic parametric maps has been demonstrated by several different pulse sequences and calibration procedures. The vital roles of sodium ion in membrane transport and the extracellular matrix will be reviewed to indicate the broad opportunities that now exist for clinical sodium MR imaging. The final challenge is for the technology to be supplied on clinical ≥3T scanners.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.