Observational studyAcademic pediatrics2017
A Clinical Score to Predict Appendicitis in Older Male Children.
Observational study in Academic pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 19 citations in OpenAlex.
- Comparison of the Alvarado Score with Alternative Diagnostic Tools in Pediatric Acute Appendicitis: A Literature Review.Pediatric reports · 2026Review
- Development of a new predictive clinico-biological score for acute appendicitis in the pediatric population.BMC surgery · 2025Article
- Many diagnostic tools for appendicitis: a scoping review.Surgical endoscopy · 2023Article
- Accuracy Evaluation of Pediatric Appendicitis Scoring (PAS) Method in Differentiating Nonspecific Abdominal Pain from Appendicitis.International journal of preventive medicine · 2023Article
- Comparison of Appendicitis Inflammatory Response (AIR) and Lintula scoring systems in diagnosing acute appendicitis among children.Journal of medicine and life · 2022Article
- Ruling out Appendicitis in Children: Can We Use Clinical Prediction Rules?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Review
- The Jumping Up (J-Up) Test: Making the Diagnosis of Acute Appendicitis Easier in Children.Global pediatric health · 2019Article
- Development and Validation of a Novel Pediatric Appendicitis Risk Calculator (pARC).Pediatrics · 2018Article
- Retrospective Multivariate Analysis of Data from Children with Suspected Appendicitis: A New Tool for Diagnosis.Emergency medicine international · 2018Article
- Which One is Better? Comparison of the Acute Inflammatory Response, Raja Isteri Pengiran Anak Saleha Appendicitis and Alvarado Scoring Systems.Annals of coloproctology · 2017Article
- Comparison of the appendicitis inflammatory response and Alvarado scoring systems in the diagnosis of acute appendicitis in children.Journal of medicine and lifeArticle
Corrections and comments
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Authors and funding
12 authors at 10 institutions in 1 country.
Funding
Abstract
objectiveTo develop a clinical score to predict appendicitis among older, male children who present to the emergency department with suspected appendicitis.
methodsPatients with suspected appendicitis were prospectively enrolled at 9 pediatric emergency departments. A total of 2625 patients enrolled; a subset of 961 male patients, age 8-18 were analyzed in this secondary analysis. Outcomes were determined using pathology, operative reports, and follow-up calls. Clinical and laboratory predictors with <10% missing data and kappa > 0.4 were entered into a multivariable model. Resultant β-coefficients were used to develop a clinical score. Test performance was assessed by calculating the sensitivity, specificity, positive predictive value, negative predictive value, and likelihood ratios.
resultsThe mean age was 12.2 years; 49.9% (480) had appendicitis, 22.3% (107) had perforation, and the negative appendectomy rate was 3%. In patients with and without appendicitis, overall imaging rates were 68.6% (329) and 84.4% (406), respectively. Variables retained in the model included maximum tenderness in the right lower quadrant, pain with walking/coughing or hopping, and the absolute neutrophil count. A score ≥8.1 had a sensitivity of 25% (95% confidence interval [CI], 20%-29%), specificity of 98% (95% CI, 96%-99%), and positive predictive value of 93% (95% CI, 86%-97%) for ruling in appendicitis.
conclusionsWe developed an accurate scoring system for predicting appendicitis in older boys. If validated, the score might allow clinicians to manage a proportion of male patients without diagnostic imaging.
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