ReviewNeuroscience and biobehavioral reviews2017
Developmental toxicity of nicotine: A transdisciplinary synthesis and implications for emerging tobacco products.
Review in Neuroscience and biobehavioral reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
97 citing papers in PubMed, 1 synthesis or guideline pooled it, 177 citations in OpenAlex.
- A Systematic Literature Review of E-Cigarette-Related Illness and Injury: Not Just for the Respirologist.International journal of environmental research and public health · 2020Pooled it
- Nicotine Ingestion Reduces Heart Rate Variability in Young Healthy Adults.BioMed research international · 2022Trial
- Trial
- Nicotine Exposure During Gestation: From Placental Dysfunction to Long-Term Neurobehavioral Outcomes.Birth defects research · 2026Review
- Electronic Smoking Devices Among University Students: Usage Patterns and Chemical Composition of Inhaled Substances.Analytical science advances · 2026Article
- Female smokers' perspectives on tobacco use and smoking cessation: a qualitative study guided by health belief model.NPJ primary care respiratory medicine · 2026Article
- Adapting and Implementing a School-Based "Implementation Intentions" Program Within FRESHAIR4Life to Prevent Smoking Initiation Among Adolescents in Greece: A Study Protocol.Healthcare (Basel, Switzerland) · 2026Article
- Adverse Physical Consequences of Perinatal E-cigarette Use by Pregnant Mothers on Their Offspring: A Scoping Review.Cureus · 2026Review
- Vaping during pregnancy and maternal, fetal, and infant health outcomes: A scoping review of human and animal studies.PloS one · 2026Article
- Menthol Cigarette Use in US Pregnancies: Prevalence, Racial and Ethnic Disparities, and Associated Characteristics from the 2010-2019 National Survey on Drug Use and Health (NSDUH).Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Histologic Chorioamnionitis and Neurodevelopment in Preterm Infants.JAMA network open · 2025Article
- Healthier lifestyles can modify the air pollutants effect on cardiovascular disease among the middle-aged and elderly.Scientific reports · 2025Article
- Demographic Characteristics Associated With Adolescent Receipt of Provider E-Cigarette Screening and Advice and the Impact on Harm Perception.AJPM focus · 2025Article
- World no-tobacco: effects of second-hand smoke (SHS) and vapors on the developing and adult brain.Frontiers in pharmacology · 2025Review
- Knowledge and perceptions of nicotine, smoking cessation and electronic nicotine delivery systems among physicians and pharmacists in a Swiss hospital group.Tobacco induced diseases · 2025Article
- Article
- Changes in U.S. Adolescent Nicotine Vaping Prevalence From 2022 to 2023: The Role of Reduced Initiation Three Years Earlier During the Onset of the Pandemic.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2024Article
- Neonicotinoid pesticides: evidence of developmental neurotoxicity from regulatory rodent studies.Frontiers in toxicology · 2024Article
- Current status and future prospects of pretreatment for tobacco stalk lignocellulose.Frontiers in bioengineering and biotechnology · 2024Review
- Perception of e-cigarette control policies and education in schools on increased legal knowledge, harm perception, susceptibility and e-cigarette use among students in Thailand: A cross-sectional classroom-based survey.Tobacco induced diseases · 2024Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 17 institutions in 2 countries.
Funding
Abstract
While the health risks associated with adult cigarette smoking have been well described, effects of nicotine exposure during periods of developmental vulnerability are often overlooked. Using MEDLINE and PubMed literature searches, books, reports and expert opinion, a transdisciplinary group of scientists reviewed human and animal research on the health effects of exposure to nicotine during pregnancy and adolescence. A synthesis of this research supports that nicotine contributes critically to adverse effects of gestational tobacco exposure, including reduced pulmonary function, auditory processing defects, impaired infant cardiorespiratory function, and may contribute to cognitive and behavioral deficits in later life. Nicotine exposure during adolescence is associated with deficits in working memory, attention, and auditory processing, as well as increased impulsivity and anxiety. Finally, recent animal studies suggest that nicotine has a priming effect that increases addiction liability for other drugs. The evidence that nicotine adversely affects fetal and adolescent development is sufficient to warrant public health measures to protect pregnant women, children, and adolescents from nicotine exposure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.