Evidence map›Paper›PMID 27890480›Full record

ArticleVascular pharmacology2017

Chemerin-induced arterial contraction is G

David J Ferland, Emma S Darios, Richard R Neubig, Benita Sjögren, Nguyen Truong, Rosa Torres, Thomas S Dexheimer, Janice M Thompson, Stephanie W Watts

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vascular pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Chemerin/ChemerinR1 axis and inflammation-related diseases.Frontiers in molecular biosciences · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Chemerin as a Driver of Hypertension: A Consideration.American journal of hypertension · 2020
    Review
  18. Adipokines and Inflammation: Focus on Cardiovascular Diseases.International journal of molecular sciences · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

David J FerlandDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States. Electronic address: ferlandd@msu.edu.
Emma S DariosDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Richard R NeubigDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Benita SjögrenDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Nguyen TruongDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Rosa TorresDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Thomas S DexheimerDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Janice M ThompsonDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Stephanie W WattsDepartment of Pharmacology and Toxicology, 1355 Bogue Street Rm B445, Michigan State University, East Lansing, MI 48824-1317, United States.
Michigan State University · US

Funding

Chemerin As a Link Between Obesity and Blood PressureR01HL117847 · NHLBI · MICHIGAN STATE UNIVERSITY · PI WATTS, STEPHANIE W · 2014 to 2017
$1.7M
NHLBI NIH HHS R01 HL117847
6 · The paper itself

Abstract

Chemerin is an adipokine associated with increased blood pressure, and may link obesity with hypertension. We tested the hypothesis that chemerin-induced contraction of the vasculature occurs via calcium flux in smooth muscle cells. Isometric contraction of rat aortic rings was performed in parallel with calcium kinetics of rat aortic smooth muscle cells to assess the possible signaling pathway. Chemerin-9 (nonapeptide of the chemerin S

Indexed as

AnimalsAortaCalciumCalcium Channels, L-TypeChemokinesDose-Response Relationship, DrugGTP-Binding Protein alpha Subunits, Gi-GoHypertensionIntercellular Signaling Peptides and ProteinsMaleMuscle ContractionMuscle, Smooth, VascularMyocytes, Smooth MuscleRatsRats, Sprague-Dawleyrho-Associated KinasesCalciumCalcium Channels, L-TypeChemokinesGTP-Binding Protein alpha Subunits, Gi-GoIntercellular Signaling Peptides and ProteinsRarres2 protein, ratrho-Associated KinasesChemerinSignalingSmooth muscle

Identifiers

PMID27890480
PMCPMC5235970
OpenAlexW2553849466

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.