Evidence map›Paper›PMID 27889808›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Pharmacodynamic evaluation of Lys

F Aura Kullmann, M Katofiasc, K B Thor, Lesley Marson

Open access · greenAbstract read
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Recent Developments in On-Demand Voiding Therapies.The Journal of pharmacology and experimental therapeutics · 2024
    Review
  2. Review
  3. [LysJournal of basic and clinical physiology and pharmacology · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Colorectal and cardiovascular effects of [LysNaunyn-Schmiedeberg's archives of pharmacology · 2018
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

F Aura KullmannDepartment of Medicine, Renal Division, University of Pittsburgh, 3500 Terrace St, Scaife A1220, Pittsburgh, PA, 15261, USA.ORCID http://orcid.org/0000-0001-6625-2946
M KatofiascDignify Therapeutics LLC, 2 Davis Drive, PO Box 13169, Research Triangle Park, NC, 27709, USA.
K B ThorDignify Therapeutics LLC, 2 Davis Drive, PO Box 13169, Research Triangle Park, NC, 27709, USA.
Lesley MarsonDignify Therapeutics LLC, 2 Davis Drive, PO Box 13169, Research Triangle Park, NC, 27709, USA. lmarson@dignifytherapeutics.com.
Triangle · USUniversity of Pittsburgh · US

Funding

Development of a treatment for voiding dysfunction in spinal cord injured patientsR44HD080263 · NICHD · DIGNIFY THERAPEUTICS, LLC · PI MARSON, LESLEY · 2016 to 2017
$1.5M
Development of a treatment for voiding dysfunction in spinal cord injured patientR43HD080263 · NICHD · DIGNIFY THERAPEUTICS, LLC · PI MARSON, LESLEY · 2014 to 2014
$159k
WATER AND SODIUM BALANCE IN CHRONIC DIALYSIS PATIENTSM01RR000035 · NCRR · JOHNS HOPKINS UNIVERSITY · PI MILLER, EDWARD D · 1985 to 1996
–
HSRD VA CDP 13-003NCRR NIH HHS M01 RR000035NICHD NIH HHS R43 HD080263NICHD NIH HHS R44 HD080263
6 · The paper itself

Abstract

The purpose of this study was to determine feasibility of a novel therapeutic approach to drug-induced voiding after spinal cord injury (SCI) using a well-characterized, peptide, neurokinin 2 receptor (NK

Indexed as

AnimalsColonDisease Models, AnimalDose-Response Relationship, DrugFeasibility StudiesFemaleGastrointestinal MotilityIndolesMuscle ContractionNeurokinin APeptide FragmentsPiperidinesPressureRats, Sprague-DawleyReceptors, Neurokinin-2Spinal Cord InjuriesGR 159897IndolesNeurokinin Aneurokinin A (4-10), Lys(5)-MeLeu(9)-Nle(10)-Peptide FragmentsPiperidinesReceptors, Neurokinin-2BladderColorectal pressureCystometryNeurokinin 2 agonistSpinal cord injury

Identifiers

PMID27889808
PMCPMC5512890
OpenAlexW2555041708

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.