ArticleNeuropharmacology2017
Pramipexole enhances disadvantageous decision-making: Lack of relation to changes in phasic dopamine release.
Abstract read
In one paragraph
Article in Neuropharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Cognitive functions of the GPe.Trends in neurosciences · 2026Review
- Steroid 5α-reductases in the brain: From neurosteroidogenesis to therapeutic implications.Frontiers in neuroendocrinology · 2026Review
- The role of neuroactive steroids in psychiatric and neurological disorders: Neurobiology and therapeutic perspectives.Neuroscience and biobehavioral reviews · 2025Review
- Impulsive-compulsive behaviours and striatal neuroactivity in mildly parkinsonian rats under D2/3 agonist and L-DOPA treatment.NPJ Parkinson's disease · 2025Article
- Prefrontal 5α-reductase 2 mediates male-specific acute stress response.Science advances · 2025Article
- Pramipexole Hyperactivates the External Globus Pallidus and Impairs Decision-Making in a Mouse Model of Parkinson's Disease.International journal of molecular sciences · 2024Article
- Pramipexole restores behavioral inhibition in highly impulsive rats through a paradoxical modulation of frontostriatal networks.Translational psychiatry · 2024Article
- Characterization of D3 Autoreceptor Function in Whole Zebrafish Brain with Fast-Scan Cyclic Voltammetry.ACS chemical neuroscience · 2022Article
- Neuroscience and actometry: An example of the benefits of the precise measurement of behavior.Brain research bulletin · 2022Review
- The steroidogenic inhibitor finasteride reverses pramipexole-induced alterations in probability discounting.Brain research bulletin · 2022Article
- The Use of Pramipexole to Treat Persistent Genital Arousal Disorder: A Case Report.Sexual medicine · 2021Article
- The adverse effects of pramipexole on probability discounting are not reversed by acute DEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2020Article
- What drugs modify the risk of iatrogenic impulse-control disorders in Parkinson's disease? A preliminary pharmacoepidemiologic study.PloS one · 2020Article
- The Steroidogenesis Inhibitor Finasteride Reduces the Response to Both Stressful and Rewarding Stimuli.Biomolecules · 2019Article
- Increased motor impulsivity in a rat gambling task during chronic ropinirole treatment: potentiation by win-paired audiovisual cues.Psychopharmacology · 2019Article
- Examining the neurochemical underpinnings of animal models of risky choice: Methodological and analytic considerations.Experimental and clinical psychopharmacology · 2019Review
- Review: brain neurobiology of gambling disorder based on rodent models.Neuropsychiatric disease and treatment · 2019Review
- Impulse control disorders in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2018Review
- Dopaminergic Neurotransmission in Patients With Parkinson's Disease and Impulse Control Disorders: A Systematic Review and Meta-Analysis of PET and SPECT Studies.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Romina PesDept. of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, United States; Dept. of Biomedical Sciences, Neuroscience Division, University of Cagliari, Italy.
Sean C GodarDept. of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, United States; Dept. of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, UT, United States.
Andrew T FoxDept. of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, United States.
Lauren M BurgenoDept. of Pharmacology, University of Washington, Seattle, WA, United States.
Hunter J StrathmanDept. of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, UT, United States.
David P JarmolowiczProblem Gambling Research Studies (ProGResS) Network, University of Kansas, Lawrence, KS, United States; Dept. of Applied Behavioral Science, University of Kansas, Lawrence, KS, United States.
Paola DevotoDept. of Biomedical Sciences, Neuroscience Division, University of Cagliari, Italy.
Beth LevantDept. of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS, United States.
Paul E PhillipsDept. of Pharmacology, University of Washington, Seattle, WA, United States; Dept. of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Stephen C FowlerDept. of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, United States.
Marco BortolatoDept. of Pharmacology and Toxicology, University of Kansas, Lawrence, KS, United States; Problem Gambling Research Studies (ProGResS) Network, University of Kansas, Lawrence, KS, United States; Dept. of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, UT, United States. Electronic address: marco.bortolato@utah.edu.
University of Kansas · USUniversity of Washington · USUniversity of Cagliari · ITUniversity of Kansas Medical Center · USUniversity of Utah · US
Funding
Research Design and Analysis Core (RDAC)P30HD002528 · NICHD · UNIVERSITY OF KANSAS LAWRENCE · PI FOWLER, STEPHEN CLETIUS · 1985 to 2015
$22.1MUnderstanding the mechanobiology of stem cells in a microengineered 3D cardiac tissue environment with cardiomyopathyP20GM103638 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI HOLMSTROM, ERIK D · 2012 to 2021
$22.1MHeartland Institute for Clinical and Translational ResearchUL1TR000001 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2012 to 2015
$13.0MDeciphering gene-environment interactions in pathological reactive aggressionR01MH104603 · NIMH · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Marco Bortolato, Regina A. Mangieri · 2014 to 2026
$6.0MHEARTLAND INSTITUTE FOR CLINICAL AND TRANSLATIONAL RESEARCHUL1RR033179 · NCRR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2011 to 2011
$3.2MDiametric changes in phasic dopamine to contingent and non-contingent drug cues in the regulation of drug taking and drug seekingR01DA039687 · NIDA · UNIVERSITY OF WASHINGTON · PI PHILLIPS, PAUL E. M. · 2015 to 2019
$1.7MNCATS NIH HHS UL1 TR000001NCRR NIH HHS UL1 RR033179NICHD NIH HHS P30 HD002528NIDA NIH HHS R01 DA039687NIGMS NIH HHS P20 GM103638NIMH NIH HHS R01 MH104603
Abstract
Pramipexole (PPX) is a high-affinity D
Indexed as
Risk-TakingAnimalsBenzothiazolesCaudate NucleusDecision MakingDopamineMaleNorepinephrineNucleus AccumbensParkinson DiseasePramipexolePrefrontal CortexProbabilityPutamenRatsRats, Long-EvansBenzothiazolesDopamineNorepinephrinePramipexoleReceptors, Dopamine D2SerotoninDopamineNucleus accumbensPramipexoleProbability discountingRisk taking
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.