Evidence map›Paper›PMID 27889455›Full record

ArticleBioorganic & medicinal chemistry letters2017

In vivo evaluation of [

Jaya Prabhakaran, Kiran Kumar Solingapuram Sai, Francesca Zanderigo, Harry Rubin-Falcone, Matthew J Jorgensen, Jay R Kaplan, Katharine I Tooke, Akiva Mintz, J John Mann, J S Dileep Kumar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioorganic & medicinal chemistry letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Radiotracers for the Central Serotoninergic System.Pharmaceuticals (Basel, Switzerland) · 2022
    Review
  2. Article
  3. In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2019
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jaya PrabhakaranDepartment of Psychiatry, Columbia University Medical Center, New York, USA; Molecular Imaging and Neuropathology Division, New York State Psychiatric Institute, New York, USA.
Kiran Kumar Solingapuram SaiDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Francesca ZanderigoDepartment of Psychiatry, Columbia University Medical Center, New York, USA; Molecular Imaging and Neuropathology Division, New York State Psychiatric Institute, New York, USA.
Harry Rubin-FalconeDepartment of Psychiatry, Columbia University Medical Center, New York, USA.
Matthew J JorgensenDepartment of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Jay R KaplanDepartment of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Katharine I TookeDepartment of Psychiatry, Columbia University Medical Center, New York, USA.
Akiva MintzDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
J John MannDepartment of Psychiatry, Columbia University Medical Center, New York, USA; Molecular Imaging and Neuropathology Division, New York State Psychiatric Institute, New York, USA.
J S Dileep KumarMolecular Imaging and Neuropathology Division, New York State Psychiatric Institute, New York, USA. Electronic address: kumardi@nyspi.columbia.edu.

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Vervet Research Colony as a Biomedical ResourceP40OD010965 · OD · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Matthew Jorgensen · 2012 to 2026
$14.6M
Wake Forest Clinical and Translational Science AwardKL2TR001421 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MILLER, DAVID P · 2015 to 2023
$5.8M
Evaluation of an [F-18] Agonist PET Ligand for 5HT2ARR21DA041670 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI PRABHAKARAN, JAYA · 2016 to 2017
$459k
NCATS NIH HHS KL2 TR001421NCATS NIH HHS UL1 TR001420NIDA NIH HHS R21 DA041670NIH HHS P40 OD010965
6 · The paper itself

Abstract

We recently reported the radiosynthesis and in vitro evaluation of [

Indexed as

Positron-Emission TomographyAnimalsChlorocebus aethiopsDose-Response Relationship, DrugEthylaminesFluorine RadioisotopesHumansLigandsMagnetic Resonance ImagingMaleMolecular StructureReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AgonistsStructure-Activity Relationship((18)F)-2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-(2-fluoroethoxy)benzyl)ethanamineEthylaminesFluorine RadioisotopesLigandsReceptor, Serotonin, 5-HT2AReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor Agonists5-HT5-HT(2A/2C)RAgonistPETRadiotracer

Identifiers

PMID27889455
PMCPMC5348621

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.