Evidence map›Paper›PMID 27889329›Full record

ReviewPharmacology & therapeutics2017

Perivascular cells and tissue engineering: Current applications and untapped potential.

Elisa Avolio, Valeria V Alvino, Mohamed T Ghorbel, Paola Campagnolo

Abstract readReview
In one paragraph

Review in Pharmacology & therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Transcriptomic Profiling Unveils EDN3Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Advancements in the Application of scRNA-Seq in Breast Research: A Review.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Sourcing cells forFrontiers in medical technology · 2022
    Review
  17. Article
  18. Natural polymer-based scaffolds for soft tissue repair.Frontiers in bioengineering and biotechnology · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elisa AvolioDivision of Experimental Cardiovascular Medicine, Bristol Heart Institute, University of Bristol, United Kingdom.
Valeria V AlvinoDivision of Experimental Cardiovascular Medicine, Bristol Heart Institute, University of Bristol, United Kingdom.
Mohamed T GhorbelDivision of Congenital Heart Surgery, Bristol Heart Institute, University of Bristol, United Kingdom.
Paola CampagnoloSchool of Biosciences and Medicine, University of Surrey, Guildford, United Kingdom. Electronic address: p.campagnolo@surrey.ac.uk.

Funding

British Heart Foundation PG/10/81/28606British Heart Foundation PG/15/32/31398British Heart Foundation RM/13/2/30158Medical Research Council MR/N027086/1
6 · The paper itself

Abstract

The recent development of tissue engineering provides exciting new perspectives for the replacement of failing organs and the repair of damaged tissues. Perivascular cells, including vascular smooth muscle cells, pericytes and other tissue specific populations residing around blood vessels, have been isolated from many organs and are known to participate to the in situ repair process and angiogenesis. Their potential has been harnessed for cell therapy of numerous pathologies; however, in this Review we will discuss the potential of perivascular cells in the development of tissue engineering solutions for healthcare. We will examine their application in the engineering of vascular grafts, cardiac patches and bone substitutes as well as other tissue engineering applications and we will focus on their extensive use in the vascularization of engineered constructs. Additionally, we will discuss the emerging potential of human pericytes for the development of efficient, vascularized and non-immunogenic engineered constructs.

Indexed as

AnimalsBiocompatible MaterialsBlood VesselsCell- and Tissue-Based TherapyHumansMuscle, Smooth, VascularMyocytes, Smooth MuscleNeovascularization, PhysiologicPericytesTissue EngineeringBiocompatible MaterialsBiomaterialsPericytesPerivascular cellsScaffold vascularizationTissue engineeringVascular graft

Identifiers

PMID27889329
PMCPMC5345698

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.