Evidence map›Paper›PMID 27889034›Full record

ReviewSurgical oncology clinics of North America2017

Human Immunodeficiency Virus/AIDS, Human Papillomavirus, and Anal Cancer.

Chia-Ching J Wang, Joseph Sparano, Joel M Palefsky

Abstract readReview
In one paragraph

Review in Surgical oncology clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.

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  20. The Role of Inflammation in Anal Cancer.Diseases (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Chia-Ching J WangDivision of Hematology/Oncology, Department of Medicine, Zuckerberg San Francisco General Hospital, 995 Potrero Avenue, Building 80, 4th Floor, San Francisco, CA 94110, USA.
Joseph SparanoDepartment of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, 1695 Eastchester Road, Bronx, NY 10461, USA.
Joel M PalefskyDivision of Infectious Diseases, Department of Medicine, University of California at San Francisco, 513 Parnassus Avenue, Medical Science Room 420E, Box 0654, San Francisco, CA 94143, USA. Electronic address: joel.palefsky@ucsf.edu.
Albert Einstein College of Medicine · USSan Francisco General Hospital · USUniversity of California San Francisco Medical Center · US

Funding

Consortium for Advancing Management and Prevention of Cancer in People with HIVUM1CA121947 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Joseph A. Sparano · 2015 to 2026
$253.7M
Anal HPV Infection and ASIL in HIV+ and HIV- WomenR01CA088739 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PALEFSKY, JOEL MICHAEL · 2001 to 2006
$5.5M
(PQ4) Anal HPV infection and anal HSIL among HIV-infected MSM aged 50+ yearsR01CA206477 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PALEFSKY, JOEL MICHAEL · 2016 to 2021
$3.4M
NCI NIH HHS R01 CA088739NCI NIH HHS R01 CA206477NCI NIH HHS UM1 CA121947
6 · The paper itself

Abstract

Anal cancer is an increasingly common non-AIDS-defining cancer among individuals infected with the human immunodeficiency virus (HIV). It is associated with human papillomavirus (HPV). HPV16 is the most common genotype detected in anal cancers. The HPV types detected in anal cancer are included in the 9-valent vaccine. HPV vaccines have demonstrated efficacy in reducing anal precancerous lesions in HIV-infected individuals. Standard treatment has been fluorouracil and mitomycin (or cisplatin) plus radiation. Continued studies are needed to test new treatment strategies in HIV-infected patients with anal cancer to determine which treatment protocols provide the best therapeutic index.

Indexed as

Acquired Immunodeficiency SyndromeAnal CanalAnus NeoplasmsHIVHIV SeropositivityHumansImmunocompromised HostImmunosuppression TherapyPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesPapillomavirus VaccinesAnal cancerHIVHPVHPV vaccinationImmunosuppression

Identifiers

PMID27889034
PMCPMC5331942
OpenAlexW2552741060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.