ArticleRice (New York, N.Y.)2016
OsWRKY80-OsWRKY4 Module as a Positive Regulatory Circuit in Rice Resistance Against Rhizoctonia solani.
Article in Rice (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 134 citations in OpenAlex.
- Pooled it
- Functional and regulatory complexity: challenges and prospects for understanding rice WRKY transcription factors.Journal of experimental botany · 2026Review
- The Transcription Factor OsWRKY30 Regulates Rice Resistance to Southern Rice Black Streaked Dwarf Virus Disease.Rice (New York, N.Y.) · 2026Article
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- Mechanism Analysis ofInternational journal of molecular sciences · 2025Article
- WRKY36-PIL15 Transcription Factor Complex Negatively Regulates Sheath Blight Resistance and Seed Development in Rice.Plants (Basel, Switzerland) · 2025Article
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- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- Screening, identification and evaluation of an acidophilic strain ofFrontiers in plant science · 2024Article
- Comparison of Transcriptome between Tolerant and Susceptible Rice Cultivar Reveals Positive and Negative Regulators of Response toInternational journal of molecular sciences · 2023Article
- RNA-Seq and Comparative Transcriptomic Analyses of Asian Soybean Rust Resistant and Susceptible Soybean Genotypes Provide Insights into Identifying Disease Resistance Genes.International journal of molecular sciences · 2023Article
- NativePlants (Basel, Switzerland) · 2023Article
- The Cytosolic Acetoacetyl-CoA Thiolase TaAACT1 Is Required for Defense againstInternational journal of molecular sciences · 2023Article
- Progress in rice sheath blight resistance research.Frontiers in plant science · 2023Review
- Genome and Transcriptome-Wide Analysis ofInternational journal of molecular sciences · 2022Article
- Role of PsnWRKY70 in Regulatory Network Response to Infection withInternational journal of molecular sciences · 2022Article
- Genomic regions and candidate genes selected during the breeding of rice in Vietnam.Evolutionary applications · 2022Article
- Ammonium transporter 1 increases rice resistance to sheath blight by promoting nitrogen assimilation and ethylene signalling.Plant biotechnology journal · 2022Article
- Lilium regale Wilson WRKY3 modulates an antimicrobial peptide gene, LrDef1, during response to Fusarium oxysporum.BMC plant biology · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlant WRKY transcription factors play pivotal roles in diverse biological processes but most notably in plant defense response to pathogens. Sheath blight represents one of the predominant diseases in rice. However, our knowledge about the functions of WRKY proteins in rice defense against sheath blight is rather limited.
resultsHere we demonstrate that the expression of Oryza sativa WRKY80 gene (OsWRKY80) is rapidly and strongly induced upon infection of Rhizoctonia solani, the causal agent of rice sheath blight disease. OsWRKY80 expression is also induced by exogenous jasmonic acid (JA) and ethylene (ET), but not by salicylic acid (SA). OsWRKY80-GFP is localized in the nuclei of onion epidermal cells in a transient expression assay. Consistently, OsWRKY80 exhibits transcriptional activation activity in a GAL4 assay in yeast cells. Overexpression of OsWRKY80 in rice plants significantly enhanced disease resistance to R. solani, concomitant with elevated expression of OsWRKY4, another positive regulator in rice defense against R. solani. Suppression of OsWRKY80 by RNA interference (RNAi), on the other hand, compromised disease resistance to R. solani. Results of yeast one-hybrid assay and transient expression assay in tobacco cells have revealed that OsWRKY80 specifically binds to the promoter regions of OsWRKY4, which contain W-box (TTGAC[C/T]) or W-box like (TGAC[C/T]) cis-elements.
conclusionsWe propose that OsWRKY80 functions upstream of OsWRKY4 as an important positive regulatory circuit that is implicated in rice defense response to sheath blight pathogen R. solani.
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