Evidence map›Paper›PMID 27888003›Full record

ReviewMolecular and cellular endocrinology2017

Small non-coding RNAs-based bone regulation and targeting therapeutic strategies.

Ying Yang, Sijie Fang

Open access · greenAbstract readReview
In one paragraph

Review in Molecular and cellular endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

  1. Co-g-CJournal of fluorescence · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Regulation of osteoclast-mediated bone resorption by microRNA.Cellular and molecular life sciences : CMLS · 2022
    Review
  8. Review
  9. Review
  10. MicroRNA-21: An Emerging Player in Bone Diseases.Frontiers in pharmacology · 2021
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ying YangDepartment of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China.
Sijie FangDepartment of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China. Electronic address: fangsijie89@hotmail.com.
Shanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small non-coding RNAs, which are 20-25 nucleotide ribonucleic acids, have emerged as an important transformation in the biological evolution over almost three decades. microRNAs (miRNAs) and short interfering RNAs (siRNAs) are two significant categories of the small RNAs that exert important effects on bone endocrinology and skeletology. Therefore, clarifying the expression and function of these important molecules in bone endocrine physiology and pathology is of great significance for improving their potential therapeutic value for metabolism-associated bone diseases. In the present review, we highlight the recent advances made in understanding the function and molecular mechanism of these small non-coding RNAs in bone metabolism, especially their potentially therapeutic values in bone-related diseases.

Indexed as

Activating Transcription Factor 4Animalsbeta CateninBone and BonesBone NeoplasmsCore Binding Factor Alpha 1 SubunitGene Expression RegulationHumansMicroRNAsMolecular Targeted TherapyOsteoarthritisOsteoblastsOsteoporosisRNA, Small InterferingSignal TransductionSp7 Transcription FactorActivating Transcription Factor 4ATF4 protein, humanbeta CateninCore Binding Factor Alpha 1 SubunitCTNNB1 protein, humanMicroRNAsRNA, Small InterferingRUNX2 protein, humanSP7 protein, humanSp7 Transcription FactorBone metabolismmiRNAsiRNATargeting therapeutics

Identifiers

PMID27888003
PMCPMC7116989
OpenAlexW2549614859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.