ArticleReproductive biomedicine online2017
Does elevated progesterone on day of oocyte maturation play a role in the racial disparities in IVF outcomes?
Article in Reproductive biomedicine online, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 25 citations in OpenAlex.
- High ovarian responders have the highest risk of premature progesterone rise.JBRA assisted reproduction · 2024Article
- Progesterone levels on hCG day and oocyte maturation in a Mexican IVF program.JBRA assisted reproduction · 2024Observational
- Moving toward Narrowing the United States Gap in Assisted Reproductive Technology (ART) Racial and Ethnic Disparities in the Next Decade.Journal of clinical medicine · 2024Review
- Inequities in Medically Assisted Reproduction: a Scoping Review.Reproductive sciences (Thousand Oaks, Calif.) · 2023Article
- Comparison of the predictive value of progesterone-related indicators for pregnancy outcomes of women undergoing the short-acting GnRH agonist long protocol: a retrospective study.Journal of ovarian research · 2021Article
- Considering race in the administration of fertility preservation. A commentary on: "Equal opportunity for all? An analysis of race and ethnicity in fertility preservation in a major American city".Journal of assisted reproduction and genetics · 2020Article
- Revisiting debates of premature luteinization and its effect on assisted reproductive technology outcome.Journal of assisted reproduction and genetics · 2019Review
- The curious case of premature luteinization.Journal of assisted reproduction and genetics · 2018Review
- Adverse effect of prematurely elevated progesterone in in vitro fertilization cycles: a literature review.Biology of reproduction · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
The aim of this study was to evaluate if premature progesterone elevation on the last day of assisted reproduction technique stimulation contributes to racial disparities in IVF outcome. A total of 3289 assisted reproduction technique cycles were evaluated in Latino, Asian, African American, and white women. Live birth was more likely in white women (42.6%) compared with Asian (34.8%) and African American women (36.3%), but was similar to Latino women (40.7%). In all racial groups, progesterone was negatively associated with live birth and the negative effect of progesterone persisted when adjusting for confounders. Although the effect of elevated progesterone was similar in all racial groups, the prevalence of elevated progesterone differed. Progesterone > 1.5 ng/ml occurred in only 10.6% of cycles in white women compared with 18.0% in Latino and 20.2% in Asian women. Progesterone > 2 ng/ml occurred in only 2.3% of cycles in white women compared with 6.3% in Latino, 5.9% in Asian and 4.4% in African American women. The increased prevalence of premature elevated progesterone persisted when controlling for IVF stimulation parameters. In conclusion, premature progesterone elevation had a negative effect on live birth in all racial groups studied. The prevalence of elevated progesterone was higher in racial minorities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.