Evidence map›Paper›PMID 27887629›Full record

ArticleGenome biology2016

The Oxford Nanopore MinION: delivery of nanopore sequencing to the genomics community.

Miten Jain, Hugh E Olsen, Benedict Paten, Mark Akeson

Erratum issuedAbstract read
In one paragraph

Article in Genome biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 785 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
785citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

785 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Nanopore sequencing for microbiological diagnosis of bacterial pneumonia: A systematic review and meta-analysis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Pooled it
  3. Guideline
  4. Pooled it
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  7. Article
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  9. Article
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  11. Review
  12. Telomere-to-Telomere Genome Assemblies ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Whole genome sequencing analysis and functional characterization of Lacticaseibacillus rhamnosus HP-B1083.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Article

725 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Miten JainUC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA.ORCID 0000-0002-4571-3982
Hugh E OlsenUC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA.
Benedict PatenUC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA.
Mark AkesonUC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA. makeson@soe.ucsc.edu.

Funding

Training SubprojectU54HG007990 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, PATTERSON, DAVID · 2014 to 2018
$14.8M
Optimization of Processive Enzymes for DNA Sequencing using NanoporesR01HG006321 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI AKESON, MARK A · 2011 to 2013
$3.6M
Optimization of Nanopore Genomic DNA SequencingR01HG007827 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI AKESON, MARK A · 2014 to 2016
$2.2M
NHGRI NIH HHS R01 HG006321NHGRI NIH HHS R01 HG007827NHGRI NIH HHS U54 HG007990
6 · The paper itself

Abstract

Nanopore DNA strand sequencing has emerged as a competitive, portable technology. Reads exceeding 150 kilobases have been achieved, as have in-field detection and analysis of clinical pathogens. We summarize key technical features of the Oxford Nanopore MinION, the dominant platform currently available. We then discuss pioneering applications executed by the genomics community.

Indexed as

AlgorithmsNanoporesAneuploidyComputational BiologyDNAGenomicsHigh-Throughput Nucleotide SequencingHumansReproducibility of ResultsDNA

Identifiers

PMID27887629
PMCPMC5124260

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.