SynthesisBMC nephrology2016
Association of peripheral arterial disease with all-cause and cardiovascular mortality in hemodialysis patients: a meta-analysis.
Synthesis in BMC nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The prognosis of kidney transplant recipients with aorto-iliac calcification: a systematic review and meta-analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2020Pooled it
- Low Ankle-Brachial Index in Patients on Hemodialysis Is Associated with Elevated Serum Levels of Spermine Oxidase and C-Reactive Protein.Life (Basel, Switzerland) · 2026Article
- Impact of Podiatric Surveillance on Amputation Rates in Patients with Diabetes and Chronic Kidney Disease.The international journal of lower extremity wounds · 2025Article
- High Serum Galectin-3 Level as a Potential Biomarker of Peripheral Artery Disease in Patients Undergoing Hemodialysis.Reviews in cardiovascular medicine · 2024Article
- Risk of post-transplant cardiovascular events in kidney transplant recipients with preexisting aortoiliac stenosis.Clinical transplantation · 2022Article
- Association of early failure of arteriovenous fistula with mortality in hemodialysis patients.Scientific reports · 2021Article
- Prognostic Significance of Abnormal Ankle-Brachial Index Among Long-term Hemodialysis Patients in Kinshasa, the Democratic Republic of the Congo.Rambam Maimonides medical journal · 2021Article
- Article
- Prevalence, clinical characteristics, and predictors of peripheral arterial disease in hemodialysis patients: a cross-sectional study.BMC nephrology · 2019Article
- Negative correlation of serum adiponectin level with peripheral artery occlusive disease in hemodialysis patients.Tzu chi medical journalArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies have shown an association between peripheral arterial disease (PAD) and increased risk of mortality in hemodialysis (HD) patients; however, the estimates vary widely and are inconsistent. It is necessary to elucidate the degree of mortality risk for PAD patients in HD population.
methodsPubMed, EMBASE, Web of Science and Cochrane Library (from inception to September 4th, 2016) were systematically searched for cohort studies assessing the association between PAD and mortality in HD patients. We calculated the pooled risk ratios (RRs) with 95% confidence intervals (CI) of all-cause and cardiovascular (CV) mortality using random effects models. Subgroup analyses were conducted to explore the source of heterogeneity.
resultsThe search identified 2,973 potentially eligible records and 10 studies (n = 32,864) were included. Our meta-analysis revealed that PAD significantly increased the risk of all-cause mortality (RR 2.15, 95 % CI 1.67-2.77, n = 32,864) and CV mortality (RR 2.99, 95 % CI 1.66-5.38, n = 31,794) in HD patients after multivariate adjustment. Subgroup analyses showed the study design and follow-up time might be two sources of heterogeneity.
conclusionPAD may be a prognostic marker of all-cause and CV mortality in HD patients. More attention should be paid to diagnosis and management of PAD in HD patients.
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