Evidence map›Paper›PMID 27886997›Full record

ReviewRadiation protection dosimetry2016

Using Stable Free Radicals to Obtain Unique and Clinically Useful Data In Vivo in Human Subjects.

Harold M Swartz

Open access · bronzeAbstract readReview
In one paragraph

Review in Radiation protection dosimetry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Harold M SwartzEPR Center for the Study of Viable Systems at Dartmouth, Department of Radiology, Geisel School of Medicine at Dartmouth, HB 7785 One Medical Center Drive, Lebanon, NH 03756, USA Harold.Swartz@Dartmouth.edu.
Dartmouth College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper attempts to: (1) provide a critical overview of the challenges and opportunities to extend electron paramagnetic resonance (EPR) into practical applications in human subjects, based on EPR measurements made in vivo; (2) summarize the clinical applications of EPR for improving treatments in cancer, wound healing and diabetic care, emphasizing EPR's unique capability to measure tissue oxygen repeatedly and with particular sensitivity to hypoxia and (3) summarize the capabilities of in vivo EPR to measure radiation dose for triage and medical guidance after a large-scale radiation exposure. The conclusion is that while still at a relatively early stage of its development and availability, clinical applications of EPR already have demonstrated significant value and the field is likely to grow in both the extent of its applications and its impact on significant problems.

Indexed as

BiomarkersElectron Spin Resonance SpectroscopyFree RadicalsHumansOximetryOxygenRadiation DosageRadiation ProtectionRadiometryReactive Oxygen SpeciesBiomarkersFree RadicalsOxygenReactive Oxygen Species

Identifiers

PMID27886997
PMCPMC6061194
OpenAlexW2558030455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.