Evidence map›Paper›PMID 27885983›Full record

ArticleeLife2016

Klp10A, a stem cell centrosome-enriched kinesin, balances asymmetries in

Cuie Chen, Mayu Inaba, Zsolt G Venkei, Yukiko M Yamashita

Abstract read
In one paragraph

Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Cell size modulates ferroptosis susceptibility.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Cellular and molecular mechanisms of asymmetric stem cell division in tissue homeostasis.Genes to cells : devoted to molecular & cellular mechanisms · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. The developmental biology of kinesins.Developmental biology · 2021
    Review
  16. Article
  17. Principles and mechanisms of asymmetric cell division.Development (Cambridge, England) · 2020
    Review
  18. Article
  19. Article
  20. Regulation of Drosophila germline stem cells.Current opinion in cell biology · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Cuie Chen *Department of Cell and Developmental Biology, Life Sciences Institute, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, United States.
Mayu Inaba *Department of Cell and Developmental Biology, Life Sciences Institute, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, United States.
Zsolt G Venkei *Department of Cell and Developmental Biology, Life Sciences Institute, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, United States.
Yukiko M YamashitaDepartment of Cell and Developmental Biology, Life Sciences Institute, Howard Hughes Medical Institute, University of Michigan, Ann Arbor, United States.

Funding

Niche-mediated regulation of asymmetric stem cell divisionR01GM118308 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YAMASHITA, YUKIKO · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM118308
6 · The paper itself

Abstract

Asymmetric stem cell division is often accompanied by stereotypical inheritance of the mother and daughter centrosomes. However, it remains unknown whether and how stem cell centrosomes are uniquely regulated and how this regulation may contribute to stem cell fate. Here we identify Klp10A, a microtubule-depolymerizing kinesin of the kinesin-13 family, as the first protein enriched in the stem cell centrosome in

Indexed as

Cell DivisionAnimalsCentrosomeDrosophilaDrosophila ProteinsGerm CellsKinesinsMaleStem CellsDrosophila ProteinsKinesinsKLP10A protein, Drosophilaasymmetric cell divisioncentrosomedevelopmental biologyD. melanogasterstem cells

Identifiers

PMID27885983
PMCPMC5235350

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.