Evidence map›Paper›PMID 27885901›Full record

ReviewRegenerative medicine2016

The bone marrow pericyte: an orchestrator of vascular niche.

Giuseppe Mangialardi, Andrea Cordaro, Paolo Madeddu

Open access · hybridAbstract readReview
In one paragraph

Review in Regenerative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Mechanisms of Pericyte-Mediated Cancer Metastasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  20. Role ofFrontiers in cell and developmental biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Giuseppe MangialardiDivision of Experimental Cardiovascular Medicine, Bristol Heart Institute, University of Bristol, UK.
Andrea CordaroDivision of Experimental Cardiovascular Medicine, Bristol Heart Institute, University of Bristol, UK.
Paolo MadedduDivision of Experimental Cardiovascular Medicine, Bristol Heart Institute, University of Bristol, UK.
University of Bristol · GB

Funding

British Heart Foundation RG/13/17/30545
6 · The paper itself

Abstract

The concept of pericyte has been changing over years. This cell type was believed to possess only a function of trophic support to endothelial cells and to maintain vasculature stabilization. In the last years, the discovery of multipotent ability of perivascular populations led to the concept of vessel/wall niche. Likewise, several perivascular populations have been identified in animal and human bone marrow. In this review, we provide an overview on bone marrow perivascular population, their cross-talk with other niche components, relationship with bone marrow stromal stem cells, and similarities and differences with the perivascular population of the vessel/wall niche. Finally, we focus on the regenerative potential of these cells and the forthcoming challenges related to their use as cell therapy products.

Indexed as

Cell DifferentiationAnimalsBone MarrowCells, CulturedHumansMesenchymal Stem CellsPericytesStem Cell Nichebone marrowCD146endosteal nicheNestinperivascular cellvascular niche

Identifiers

PMID27885901
PMCPMC5677781
OpenAlexW2555313798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.