Evidence map›Paper›PMID 27885827›Full record

ArticleCPT: pharmacometrics & systems pharmacology2016

A Mathematical Modeling Approach to Understanding the Effect of Anti-Interleukin Therapy on Eosinophils.

T Karelina, V Voronova, O Demin, G Colice, B M Agoram

Open access · goldAbstract read
In one paragraph

Article in CPT: pharmacometrics & systems pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Effect of Src tyrosine kinase on a rat model of asthma.Experimental and therapeutic medicine · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

T KarelinaInstitute for Systems Biology, Moscow, Russia.
V VoronovaInstitute for Systems Biology, Moscow, Russia.
O DeminInstitute for Systems Biology, Moscow, Russia.
G ColiceAstrazeneca, Global Medicines Development, Gaithersburg, Maryland, USA.
B M AgoramMedImmune LLC, Clinical Pharmacology, Drug Metabolism, and Pharmacokinetics, Mountain View, California, USA.
InSysBio (Russia) · RUAstraZeneca (United States) · USSearch for Extraterrestrial Intelligence · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging T-helper type 2 (Th

Indexed as

Models, BiologicalAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedAsthmaEosinophilsHumansInterleukin-13Respiratory SystemAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedIL13 protein, humanInterleukin-13lebrikizumabmepolizumabtralokinumab

Identifiers

PMID27885827
PMCPMC5192997
OpenAlexW2550032140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.