Evidence map›Paper›PMID 27885550›Full record

ReviewCurrent topics in behavioral neurosciences

Neural Activity Patterns Underlying Spatial Coding in the Hippocampus.

Marielena Sosa, Anna K Gillespie, Loren M Frank

Abstract readReview
In one paragraph

Review in Current topics in behavioral neurosciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
  10. A consistent map in the medial entorhinal cortex supports spatial memory.bioRxiv : the preprint server for biology · 2023
    Article
  11. Systematic characterization of a non-transgenic AβBiology of sex differences · 2023
    Article
  12. Voltage-Gated NaLife (Basel, Switzerland) · 2023
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Navigating for reward.Nature reviews. Neuroscience · 2021
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marielena SosaKavli Institute for Fundamental Neuroscience and Department of Physiology, University of California, San Francisco, USA.
Anna K GillespieHoward Hughes Medical Institute, Maryland, USA.
Loren M FrankKavli Institute for Fundamental Neuroscience and Department of Physiology, University of California, San Francisco, USA. loren@phy.ucsf.edu.

Funding

Real-time analysis of memories and decisionsR01MH105174 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EDEN, URI TZVI, FRANK, LOREN M · 2014 to 2018
$2.7M
The role of hippocampal replay in memory formation and retrievalR01MH090188 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FRANK, LOREN M · 2011 to 2015
$1.9M
Howard Hughes Medical InstituteNIMH NIH HHS R01 MH090188NIMH NIH HHS R01 MH105174
6 · The paper itself

Abstract

The hippocampus is well known as a central site for memory processing-critical for storing and later retrieving the experiences events of daily life so they can be used to shape future behavior. Much of what we know about the physiology underlying hippocampal function comes from spatial navigation studies in rodents, which have allowed great strides in understanding how the hippocampus represents experience at the cellular level. However, it remains a challenge to reconcile our knowledge of spatial encoding in the hippocampus with its demonstrated role in memory-dependent tasks in both humans and other animals. Moreover, our understanding of how networks of neurons coordinate their activity within and across hippocampal subregions to enable the encoding, consolidation, and retrieval of memories is incomplete. In this chapter, we explore how information may be represented at the cellular level and processed via coordinated patterns of activity throughout the subregions of the hippocampal network.

Indexed as

AnimalsHippocampusHumansLearningNerve NetNeural PathwaysNeuronsSpatial BehaviorgammahippocampuslearningLFPmemorynetwork activityoscillationsplace cellssharp-wave ripplesspatial codingtheta

Identifiers

PMID27885550
PMCPMC5628163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.