Evidence map›Paper›PMID 27885466›Full record

ArticleParasitology research2017

Molecular epidemiology and multilocus sequence analysis of potentially zoonotic Giardia spp. from humans and dogs in Jamaica.

Mellesia F Lee, Paul Cadogan, Sarah Eytle, Sonia Copeland, Julia Walochnik, John F Lindo

Abstract read
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In one paragraph

Article in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Current research in parasitology & vector-borne diseases · 2023
    Review
  4. Zoonotic giardiasis: an update.Parasitology research · 2021
    Review
  5. Article
  6. Article
  7. Prevalence and Zoonotic Potential ofAnimals : an open access journal from MDPI · 2019
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mellesia F LeeDepartment of Microbiology, University of the West Indies, Mona, Kingston 7, Jamaica.
Paul CadoganJamaica Veterinary Medical Association, Kingston, Jamaica.
Sarah EytleJamaica Veterinary Medical Association, Kingston, Jamaica.
Sonia CopelandMinistry of Health, Kingston, Jamaica.
Julia WalochnikInstitute of Specific Prophylaxis and Tropical Medicine, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
John F LindoDepartment of Microbiology, University of the West Indies, Mona, Kingston 7, Jamaica. john.lindo@uwimona.edu.jm.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giardia spp. are the causative agents of intestinal infections in a wide variety of mammals including humans and companion animals. Dogs may be reservoirs of zoonotic Giardia spp.; however, the potential for transmission between dogs and humans in Jamaica has not been studied. Conventional PCR was used to screen 285 human and 225 dog stool samples for Giardia targeting the SSU rDNA gene followed by multilocus sequencing of the triosephosphate isomerase (tpi), glutamate dehydrogenase (gdh), and β-giardin (bg) genes. Prevalence of human infections based on PCR was 6.7 % (19/285) and canine infections 19.6 % (44/225). Nested PCR conducted on all 63 positive samples revealed the exclusive presence of assemblage A in both humans and dogs. Sub-assemblage A-II was responsible for 79.0 % (15/19) and 70.5 % (31/44) of the infections in humans and dogs, respectively, while sub-assemblage A-I was identified at a rate of 15.8 % (3/19) and 29.5 % (13/44) in humans and dogs, respectively. The predominance of a single circulating assemblage among both humans and dogs in Jamaica suggests possible zoonotic transmission of Giardia infections.

Indexed as

Multilocus Sequence TypingAnimalsCytoskeletal ProteinsDNA, RibosomalDog DiseasesDogsGene Expression RegulationGiardiaGiardia lambliaGiardiasisGlutamate DehydrogenaseHumansJamaicaMolecular EpidemiologyPhylogenyPolymerase Chain ReactionCytoskeletal ProteinsDNA, Ribosomalgiardin protein, Giardia lambliaGlutamate DehydrogenaseProtozoan ProteinsTriose-Phosphate IsomeraseAssemblagesDogsGiardiaHumansJamaicaZoonotic transmission

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.