Evidence map›Paper›PMID 27884797›Full record

ReviewRespiratory physiology & neurobiology2017

Breathing abnormalities in animal models of Rett syndrome a female neurogenetic disorder.

Chun Jiang, Ningren Cui, Weiwei Zhong, Christopher M Johnson, Yang Wu

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Respiratory physiology & neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Rett and Rett-related disorders: Common mechanisms for shared symptoms?Experimental biology and medicine (Maywood, N.J.) · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chun JiangDepartment of Biology, Georgia State University, Atlanta, USA. Electronic address: cjiang@gsu.edu.
Ningren CuiDepartment of Biology, Georgia State University, Atlanta, USA.
Weiwei ZhongDepartment of Biology, Georgia State University, Atlanta, USA.
Christopher M JohnsonDepartment of Biology, Georgia State University, Atlanta, USA.
Yang WuDepartment of Biology, Georgia State University, Atlanta, USA.
Georgia State University · US

Funding

Breathing disorders in a mouse model of Rett syndromeR01NS073875 · NINDS · GEORGIA STATE UNIVERSITY · PI JIANG, CHUN · 2011 to 2015
$1.6M
NINDS NIH HHS R01 NS073875
6 · The paper itself

Abstract

A characteristic feature of Rett syndrome (RTT) is abnormal breathing accompanied by several other neurological and cognitive disorders. Since RTT rodent models became available, studies have begun shedding insight into the breathing abnormalities at behavioral, cellular and molecular levels. Defects are found in several groups of brainstem neurons involved in respiratory control, and potential neural mechanisms have been suggested. The findings in animal models are helpful in therapeutic strategies for people with RTT with respect to lowering sudden and unexpected death, preventing secondary developmental consequences, and improving the quality of lives.

Indexed as

AnimalsDisease Models, AnimalFemaleHumansRespiration DisordersRett SyndromeAnimal modelsAutonomic functionBrainstemBreathingCO(2) chemosensitivityMecp2Rett syndrome

Identifiers

PMID27884797
PMCPMC5438903
OpenAlexW2549731316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.