Evidence map›Paper›PMID 27884691›Full record

SynthesisThe journal of pain2017

AAPT Diagnostic Criteria for Chronic Cancer Pain Conditions.

Judith A Paice, Matt Mulvey, Michael Bennett, Patrick M Dougherty, John T Farrar, Patrick W Mantyh, Christine Miaskowski, Brian Schmidt, Thomas J Smith

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in The journal of pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Non-opioid Analgesics and Emerging Therapies.Cancer treatment and research · 2021
    Pooled it
  2. Methadone versus other opioids for refractory malignant bone pain: a pilot randomised controlled study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  3. Article
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  5. Review
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  12. The role of methadone in cancer-induced bone pain: a retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Review
  18. Gastrointestinal pain.Nature reviews. Disease primers · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Judith A PaiceDivision of Hematology-Oncology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois. Electronic address: j-paice@northwestern.edu.
Matt MulveyAcademic Unit of Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom.
Michael BennettAcademic Unit of Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom.
Patrick M DoughertyThe Division of Anesthesia and Critical Care Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas.
John T FarrarDepartment of Epidemiology, Neurology, and Anesthesia, University of Pennsylvania, Philadelphia, Pennsylvania.
Patrick W MantyhDepartment of Pharmacology, University of Arizona, Tucson, Arizona.
Christine MiaskowskiDepartment of Physiological Nursing, University of California, San Francisco, California.
Brian SchmidtBluestone Center for Clinical Research, New York University College of Dentistry, New York, New York.
Thomas J SmithDepartment of Oncology, The Johns Hopkins Hospital, Baltimore, Maryland.
University of Leeds · GBCenter for Clinical Research (United States) · USJohns Hopkins Hospital · USNorthwestern University · USThe University of Texas MD Anderson Cancer Center · USUniversity of Arizona · USUniversity of California, San Francisco · USUniversity of Pennsylvania · US

Funding

The role of ENF loss, TLR4 and spinal plasticity in paclitaxel CIPNR01CA200263 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DOUGHERTY, PATRICK M · 2016 to 2020
$2.4M
NCI NIH HHS R01 CA200263
6 · The paper itself

Abstract

Chronic cancer pain is a serious complication of malignancy or its treatment. Currently, no comprehensive, universally accepted cancer pain classification system exists. Clarity in classification of common cancer pain syndromes would improve clinical assessment and management. Moreover, an evidence-based taxonomy would enhance cancer pain research efforts by providing consistent diagnostic criteria, ensuring comparability across clinical trials. As part of a collaborative effort between the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) and the American Pain Society (APS), the ACTTION-APS Pain Taxonomy initiative worked to develop the characteristics of an optimal diagnostic system. After the establishment of these characteristics, a working group consisting of clinicians and clinical and basic scientists with expertise in cancer and cancer-related pain was convened to generate core diagnostic criteria for an illustrative sample of 3 chronic pain syndromes associated with cancer (ie, bone pain and pancreatic cancer pain as models of pain related to a tumor) or its treatment (ie, chemotherapy-induced peripheral neuropathy). A systematic review and synthesis was conducted to provide evidence for the dimensions that comprise this cancer pain taxonomy. Future efforts will subject these diagnostic categories and criteria to systematic empirical evaluation of their feasibility, reliability, and validity and extension to other cancer-related pain syndromes. PERSPECTIVE: The ACTTION-APS chronic cancer pain taxonomy provides an evidence-based classification for 3 prevalent syndromes, namely malignant bone pain, pancreatic cancer pain, and chemotherapy-induced peripheral neuropathy. This taxonomy provides consistent diagnostic criteria, common features, comorbidities, consequences, and putative mechanisms for these potentially serious cancer pain conditions that can be extended and applied with other cancer-related pain syndromes.

Indexed as

Cancer PainChronic PainEvidence-Based MedicineHumansPain MeasurementPublic-Private Sector PartnershipsSocieties, MedicalUnited Statesbone painCancer painchemotherapy-induced peripheral neuropathypancreatic cancertaxonomy

Identifiers

PMID27884691
PMCPMC5439220
OpenAlexW2553540101

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.