Observational studyAtencion primaria
Estimated saving of antibiotics in pharyngitis and lower respiratory tract infections if general practitioners used rapid tests and followed guidelines.
Observational study in Atencion primaria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03540706 (Impact of the Use of C-reactive Protein in a Micro-method on the Prescription of Antibiotics in General Practitioners Consulting in the Office), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of the Use of C-reactive Protein in a Micro-method on the Prescription of Antibiotics in General Practitioners Consulting in the Office
Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Capillary CRP in primary care in France: an observational study.BMC primary care · 2025Observational
- Impact of Lung Ultrasound along with C-Reactive Protein Point-of-Care Testing on Clinical Decision-Making and Perceived Usefulness in Routine Healthcare for Patients with Lower Respiratory Tract Infections: Protocol for Analytical Observational Study.Journal of clinical medicine · 2024Article
- Cost-Effectiveness Analysis of Rapid Test Compared to Polymerase Chain Reaction (PCR) in Patients with Acute Respiratory Syndrome.Medical journal of the Islamic Republic of Iran · 2022Article
- Changes in antibiotic prescription following an education strategy for acute respiratory infections.NPJ primary care respiratory medicine · 2021Article
- [Twenty-five myths in infectious diseases in primary care associated with overdiagnosis and overtreatment].Atencion primaria · 2018Review
- Respuesta de los autores.Atencion primaria · 2018Article
- [Saving antibiotics prescribed in pharyngitis and lower respiratory tract infections in Primary Care].Atencion primaria · 2018Article
- Debunking myths: The utilisation of antibiotics in primary care in Spain.Atencion primaria · 2017Article
- Survey of Spanish general practitioners' attitudes toward management of sore throat: an internet-based questionnaire study.BMC family practice · 2017Article
- [Recommendations for the use of rapid diagnosis techniques in respiratory infections in primary care].Atencion primariaArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGeneral practitioners (GP) in Spain do not have access to rapid tests and adherence to guidelines is usually suboptimal. The aim of the study is to evaluate the estimated number of antibiotics that could have been saved if GPs had appropriately used these tests and had followed the guidelines.
designObservational study.
settingPrimary care centres from eight Autonomous Communities in Spain.
participantsGPs who had not participated in previous studies on rational use of antibiotics.
interventionGPs registered all the cases of pharyngitis and lower respiratory tract infections (LRTI) during 15 working days in 2015, by means of a 47-item audit. MAIN MEASUREMENTS: Actual GPs' antibiotic prescription and estimated number of antibiotics that could have been saved according to recent guidelines.
resultsA total of 126 GPs registered 1012 episodes of pharyngitis and 1928 LRTIs. Antibiotics were given or patients were referred in 497 patients with pharyngitis (49.1%) and 963 patients with LRTI (49.9%). If GPs had appropriately used rapid antigen detection tests and C-reactive protein tests and had strictly followed current guidelines, antibiotics would have been given to 7.6% and 15.1%, respectively, with an estimated saving of 420 antibiotics in patients with sore throat (estimated saving of 84.5%; 95% CI: 81.1-87.4%) and 672 antibiotics in LRTIs (estimated saving of 69.8%,95% CI: 67.1-72.5%).
conclusionsGP adherence to guidelines and a correct introduction of rapid tests in clinical practice in Spain could result in a considerable saving of unnecessary prescription of antibiotics in pharyngitis and LRTIs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.