Evidence map›Paper›PMID 27884420›Full record

ArticleThe American journal of cardiology2017

Referral for Specialist Follow-up and Its Association With Post-discharge Mortality Among Patients With Systolic Heart Failure (from the National Heart Failure Audit for England and Wales).

Connor A Emdin, Allan J Hsiao, Amit Kiran, Nathalie Conrad, Gholamreza Salimi-Khorshidi, Mark Woodward, Simon G Anderson, Hamid Mohseni, John J V McMurray, John G F Cleland and 4 more

Open access · hybridAbstract read
In one paragraph

Article in The American journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 38 citations in OpenAlex.

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  10. Advanced heart failure with reduced ejection fraction.Proceedings (Baylor University. Medical Center) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Connor A EmdinDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
Allan J HsiaoDepartment of Economics, University of Oxford, Oxford, United Kingdom.
Amit KiranDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
Nathalie ConradDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
Gholamreza Salimi-KhorshidiDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
Mark WoodwardDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom; The George Institute for Global Health, University of Sydney, Sydney, Australia.
Simon G AndersonDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
Hamid MohseniDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
John J V McMurrayInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
John G F ClelandDepartment of Medicine, Imperial College, London, United Kingdom.
Henry DargieInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom.
Suzanna HardmanClinical and Academic Department of Cardiovascular Medicine, Whittington Health, London, United Kingdom.
Theresa McDonaghCardiology Department, King's College Hospital, London, United Kingdom.
Kazem RahimiDepartment of Obstetrics and Gynecology, The George Institute for Global Health, University of Oxford, Oxford, United Kingdom; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom. Electronic address: kazem.rahimi@georgeinstitute.ox.ac.uk.
The George Institute for Global Health · GBUniversity of Glasgow · GBImperial College London · GBKing's College Hospital · GBThe University of Sydney · AUUniversity of Oxford · GBWhittington Health NHS Trust · GB

Funding

British Heart Foundation FS/16/10/32053Department of Health CDF-2013-06-012
6 · The paper itself

Abstract

For patients admitted with worsening heart failure (HF), early follow-up after discharge is recommended. Whether outcomes can be improved when follow-up is done by cardiologists is uncertain. We aimed to determine the association between cardiology follow-up and risk of death for patients with HF discharged from hospital. Using data from the National Heart Failure Audit (England and Wales), we investigated the effect of referral to cardiology follow-up on 30-day and 1-year mortality in 68,772 patients with HF and a reduced left ventricular ejection fraction discharged from 185 hospitals from 2007 to 2013. The primary analyses used instrumental variable analysis complemented by hierarchical logistic and propensity-matched models. At the hospital level, rates of referral to cardiologists varied from 6% to 96%. The median odds ratio (OR) for referral to cardiologist was 2.3 (95% confidence interval [CI] 2.1 to 2.5), suggesting that, on average, the odds of a patient being referred for cardiologist follow-up after discharge differed ∼2.3 times from one randomly selected hospital to another one. Based on the proportion of patients (per region) referred for cardiology follow-up, referral for cardiology follow-up was associated with lower 30-day (OR 0.70; 95% CI 0.55 to 0.89) and 1-year mortality (OR 0.81; 95% CI 0.68 to 0.95) compared with no plans for cardiology follow-up (i.e., standard follow-up done by family doctors). Results from hierarchical logistic models and propensity-matched models were consistent (30-day mortality OR 0.66; 95% CI 0.61 to 0.72 and 0.66; 95% CI 0.58 to 0.76 for hierarchical and propensity matched models, respectively). For patients with HF and a reduced left ventricular ejection fraction admitted to hospital with worsening symptoms, referral to cardiology services for follow-up after discharge is strongly associated with reduced mortality, both early and late.

Indexed as

AftercareAgedAged, 80 and overCardiologyEnglandFemaleFollow-Up StudiesHeart Failure, SystolicHospitalizationHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioPatient Discharge

Identifiers

PMID27884420
PMCPMC5282396
OpenAlexW2548385602

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.