ReviewThe Medical clinics of North America2017
The Pressure of Aging.
Review in The Medical clinics of North America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- Current Knowledge About Aprocitentan in Hypertension.International journal of molecular sciences · 2025Review
- Impact of Simulated Vascular Aging and Heart Rate on Myocardial Efficiency: A Tale of Two Paradigms from In Silico Modelling.Journal of cardiovascular development and disease · 2025Article
- Salt sensitivity and myocardial fibrosis: unraveling the silent cardiovascular remodeling.Frontiers in pharmacology · 2025Review
- Evaluation of vascular aging on measures of cardiac function and mechanical efficiency: insights fromFrontiers in cardiovascular medicine · 2024Article
- The association between arterial stiffness and cancer occurrence: Data from Kailuan cohort study.Frontiers in cardiovascular medicine · 2023Article
- The Need for Individualized Risk Assessment in Cardiovascular Disease.Journal of personalized medicine · 2022Review
- The relationship of endothelial function and arterial stiffness with subclinical target organ damage in essential hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Temporal trends in pulse pressure and mean arterial pressure in Chinese children and adolescents over two decades (1991-2015).Frontiers in cardiovascular medicine · 2022Article
- Effects of puerarin on chronic inflammation: Focus on the heart, brain, and arteries.Aging medicine (Milton (N.S.W)) · 2021Review
- Age-associated proinflammatory elastic fiber remodeling in large arteries.Mechanisms of ageing and development · 2021Review
- Vascular Aging in Rodent Models: Contrasting Mechanisms Driving the Female and Male Vascular Senescence.Frontiers in aging · 2021Review
- Magnesium and Hypertension in Old Age.Nutrients · 2020Review
- Sex Differences in Longitudinal Determinants of Carotid Intima Medial Thickening With Aging in a Community-Dwelling Population: The Baltimore Longitudinal Study on Aging.Journal of the American Heart Association · 2020Article
- Aortic remodeling is modest and sex-independent in mice when hypertension is superimposed on aging.Journal of hypertension · 2020Article
- Klotho Gene in Human Salt-Sensitive Hypertension.Clinical journal of the American Society of Nephrology : CJASN · 2020Article
- The tripartite interaction of phosphate, autophagy, and αKlotho in health maintenance.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020Article
- Two-dimensional system based on organic and functional impairment with aging for precisely assessing risk factors in chronic disease.Archives of medical science : AMS · 2020Article
- Association of soil potassium and sodium concentrations with spatial disparities of prevalence and mortality rates of hypertensive diseases in the USA.Environmental geochemistry and health · 2018Article
- Comparison of Digitalis Sensitivities of NaACS omega · 2017Article
- Aging: Molecular Pathways and Implications on the Cardiovascular System.Oxidative medicine and cellular longevity · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Significant hemodynamic changes ensue with aging, leading to an ever-growing epidemic of hypertension. Alterations in central arterial properties play a major role in these hemodynamic changes. These alterations are characterized by an initial decline in aortic distensibility and an increase of diastolic blood pressure, followed by a sharp increase in pulse wave velocity (PWV), and an increase in pulse pressure (PP) beyond the sixth decade. However, the trajectories of PWV and PP diverge with advancing age. There is an increased prevalence of salt-sensitive hypertension with advancing age that is, in part, mediated by marinobufagenin, an endogenous sodium pump ligand.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.