ArticleMalaria journal2016
Demographic and clinical profiles of Plasmodium falciparum and Plasmodium vivax patients at a tertiary care centre in southwestern India.
Article in Malaria journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Spatiotemporal epidemiology of indigenous and imported malaria cases in Goa, western India.Malaria journal · 2025Article
- Descriptive, Hospital-Based, 10-Year Study of Malaria Transmission in Goa, a Southwest Indian State in the Malaria Elimination Phase.The American journal of tropical medicine and hygiene · 2024Article
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- A fatal respiratory complication of malaria caused by Plasmodium vivax.Malaria journal · 2023Article
- Development of a Plasmodium vivax biobank for functional ex vivo assays.Malaria journal · 2023Article
- Magnitude and patterns of severeFrontiers in medicine · 2023Article
- Targeting plasmodium α-tubulin-1 to block malaria transmission to mosquitoes.Frontiers in cellular and infection microbiology · 2023Article
- Diverse Malaria Presentations across National Institutes of Health South Asia International Center for Excellence in Malaria Research Sites in India.The American journal of tropical medicine and hygiene · 2022Article
- International Center of Excellence for Malaria Research for South Asia and Broader Malaria Research in India.The American journal of tropical medicine and hygiene · 2022Article
- Optimization of Plasmodium vivax sporozoite production from Anopheles stephensi in South West India.Malaria journal · 2021Article
- A micro-epidemiological report on the unstable transmission of malaria in Aligarh, India.Parasite epidemiology and control · 2020Article
- Severe vivax malaria trends in the last two years: a study from a tertiary care centre, Delhi, India.Annals of clinical microbiology and antimicrobials · 2020Article
- Hospital-derived antibody profiles of malaria patients in Southwest India.Malaria journal · 2019Article
- ClinEpiDB: an open-access clinical epidemiology database resource encouraging online exploration of complex studies.Gates open research · 2019Article
- Article
- Evaluating Generalizability of a Biospecimen Informatics Approach: Support for Local Requirements and Best Practices.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2018Article
- Dynamics of Plasmodium vivax sporogony in wild Anopheles stephensi in a malaria-endemic region of Western India.Malaria journal · 2017Article
- An outbreak of locally acquired Plasmodium vivax malaria among migrant workers in Oman.Parasite (Paris, France) · 2017Article
- Clinical spectrum ofTropical parasitologyArticle
- Distinct genomic architecture of Plasmodium falciparum populations from South Asia.Molecular and biochemical parasitologyArticle
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40 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundMalaria remains an important cause of morbidity and mortality in India. Though many comprehensive studies have been carried out in Africa and Southeast Asia to characterize and examine determinants of Plasmodium falciparum and Plasmodium vivax malaria pathogenesis, fewer have been conducted in India.
methodsA prospective study of malaria-positive individuals was conducted at Goa Medical College and Hospital (GMC) from 2012 to 2015 to identify demographic, diagnostic and clinical indicators associated with P. falciparum and P. vivax infection on univariate analysis.
resultsBetween 2012 and 2015, 74,571 febrile individuals, 6287 (8.4%) of whom were malaria positive, presented to GMC. The total number of malaria cases at GMC increased more than two-fold over four years, with both P. vivax and P. falciparum cases present year-round. Some 1116 malaria-positive individuals (mean age = 27, 91% male), 88.2% of whom were born outside of Goa and 51% of whom were construction workers, were enroled in the study. Of 1088 confirmed malaria-positive patients, 77.0% had P. vivax, 21.0% had P. falciparum and 2.0% had mixed malaria. Patients over 40 years of age and with P. falciparum infection were significantly (p < 0.001) more likely to be hospitalised than younger and P. vivax patients, respectively. While approximately equal percentages of hospitalised P. falciparum (76.6%) and P. vivax (78.9%) cases presented with at least one WHO severity indicator, a greater percentage of P. falciparum inpatients presented with at least two (43.9%, p < 0.05) and at least three (29.9%, p < 0.01) severity features. There were six deaths among the 182 hospitalised malaria positive patients, all of whom had P. falciparum.
conclusionDuring the four year study period at GMC, the number of malaria cases increased substantially and the greatest burden of severe disease was contributed by P. falciparum.
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