Evidence map›Paper›PMID 27884113›Full record

ArticleBMC microbiology2016

Disrupting ROS-protection mechanism allows hydrogen peroxide to accumulate and oxidize Sb(III) to Sb(V) in Pseudomonas stutzeri TS44.

Dan Wang, Fengqiu Zhu, Qian Wang, Christopher Rensing, Peng Yu, Jing Gong, Gejiao Wang

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Dan WangState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Fengqiu ZhuState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Qian WangState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Christopher RensingCollege of Resources and Environment, Fujian Agriculture and Forestry University, Fuzhou, People's Republic of China.
Peng YuState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Jing GongState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China.
Gejiao WangState Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, People's Republic of China. gejiao@mail.hzau.edu.cn.
Huazhong Agricultural University · CNFujian Agriculture and Forestry University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrobial antimonite [Sb(III)] oxidation converts toxic Sb(III) into less toxic antimonate [Sb(V)] and plays an important role in the biogeochemical Sb cycle. Currently, little is known about the mechanisms underlying bacterial Sb(III) resistance and oxidation.

resultsIn this study, Tn5 transposon mutagenesis was conducted in the Sb(III)-oxidizing strain Pseudomonas stutzeri TS44 to isolate the genes responsible for Sb(III) resistance and oxidation. An insertion mutation into gshA, encoding a glutamate cysteine ligase involved in glutathione biosynthesis, generated a strain called P. stutzeri TS44-gshA

conclusionsBased on the results, we propose that a disruption of the pathway involved in ROS-protection allowed H

Indexed as

Oxidation-ReductionAntimonyBacterial ProteinsCatalaseDNA Transposable ElementsGene Expression Regulation, BacterialGenes, BacterialGlutamate-Cysteine LigaseGlutathioneHydrogen PeroxideMutagenesisMutationOxidantsPseudomonas stutzeriReactive Oxygen SpeciesStress, PsychologicalantimoniteAntimonyBacterial ProteinsCatalaseDNA Transposable ElementsGCLM protein, humanGlutamate-Cysteine LigaseGlutathioneHydrogen PeroxideOxidantsReactive Oxygen SpeciesSodB protein, BacteriaSuperoxide DismutasegshAH2O2Pseudomonas stutzeriReactive oxygen species (ROS)Sb(III) oxidationTransposon mutagenesis

Identifiers

PMID27884113
PMCPMC5123405
OpenAlexW2549394158

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.