Evidence map›Paper›PMID 27883906›Full record

ReviewCarbohydrate research2017

Infant food applications of complex carbohydrates: Structure, synthesis, and function.

Dorothy L Ackerman, Kelly M Craft, Steven D Townsend

Abstract readReview
In one paragraph

Review in Carbohydrate research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Review
  3. The Gut in Early Life-Postnatal Challenges.Children (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Review
  6. Metabolic Engineering ofChem & bio engineering · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Nutrients · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Synthesis as an Expanding Resource in Human Milk Science.Journal of the American Chemical Society · 2021
    Review
  17. Article
  18. Review
  19. Article
  20. Prebiotics metabolism by gut-isolated probiotics.Journal of food science and technology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dorothy L AckermanDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235, United States.
Kelly M CraftDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235, United States.
Steven D TownsendDepartment of Chemistry, Vanderbilt University, Nashville, TN 37235, United States; Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States. Electronic address: steven.d.townsend@vanderbilt.edu.

Funding

Chemistry-Biology Interface Training GrantT32GM065086 · NIGMS · VANDERBILT UNIVERSITY · PI BACHMANN, BRIAN O, SULIKOWSKI, GARY ALLEN · 2002 to 2022
$7.0M
NIGMS NIH HHS T32 GM065086
6 · The paper itself

Abstract

Professional health bodies such as the World Health Organization (WHO), the American Academy of Pediatrics (AAP), and the U.S. Department of Health and Human Services (HHS) recommend breast milk as the sole source of food during the first year of life. This position recognizes human milk as being uniquely suited for infant nutrition. Nonetheless, most neonates in the West are fed alternatives by 6 months of age. Although inferior to human milk in most aspects, infant formulas are able to promote effective growth and development. However, while breast-fed infants feature a microbiota dominated by bifidobacteria, the bacterial flora of formula-fed infants is usually heterogeneous with comparatively lower levels of bifidobacteria. Thus, the objective of any infant food manufacturer is to prepare a product that results in a formula-fed infant developing a breast-fed infant-like microbiota. The goal of this focused review is to discuss the structure, synthesis, and function of carbohydrate additives that play a role in governing the composition of the infant microbiome and have other health benefits.

Indexed as

Gastrointestinal MicrobiomeBifidobacteriumCarbohydrate MetabolismCarbohydratesFructansHumansInfantInfant FormulaLactoseMilk, HumanOligosaccharidesPolysaccharidesPrebioticsCarbohydratesFructanshemicelluloseLactoseOligosaccharidesPolysaccharidesPrebioticsCarrageenansCelluloseFructanFructooligosaccharideGalactomannansGalactooligosaccharideHemicelluloseInulinLactitolLactoseLactuloseLevanPolydextroseXylooligosacharide

Identifiers

PMID27883906
PMCPMC6172010

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.