Evidence map›Paper›PMID 27883374›Full record

ArticleInfection & chemotherapy2016

Association between Body Mass Index and Sputum Culture Conversion among South Korean Patients with Multidrug Resistant Tuberculosis in a Tuberculosis Referral Hospital.

Hyun Oh Park, Sung Hwan Kim, Seong Ho Moon, Joung Hun Byun, Jong Woo Kim, Chung Eun Lee, Jong Duk Kim, In Seok Jang, Jun Ho Yang

Open access · goldAbstract read
In one paragraph

Article in Infection & chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hyun Oh ParkDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, Korea.ORCID http://orcid.org/0000-0003-1302-6456
Sung Hwan KimDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Seong Ho MoonDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Joung Hun ByunDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Jong Woo KimDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Chung Eun LeeDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Hospital, Jinju, Korea.
Jong Duk KimDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Hospital, Jinju, Korea.
In Seok JangDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Hospital, Jinju, Korea.
Jun Ho YangDepartment of Thoracic and Cardiovascular Surgery, College of Medicine and Institute of Health Sciences, Gyeongsang National University Hospital, Jinju, Korea. junhoyah@hanmail.net.ORCID http://orcid.org/0000-0002-7508-5307
Changwon National University · KRGyeongsang National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultidrug-resistant tuberculosis (MDR-TB) is an important global health problem. Furthermore, the time to identify a positive sputum culture is an important risk factor for the spread of tuberculosis, and several factors can predict a prolonged time to culture conversion. Moreover, the relationship between poor nutritional status and infectious disease is clearly established. Therefore, the present study aimed to investigate the association between body mass index (BMI) and sputum culture conversion within 3 months among patients with MDR-TB. MATERIALS AND

methodsWe retrospectively evaluated 218 patients with MDR-TB who were treated at a large tuberculosis referral hospital in South Korea between January 2005 and December 2010. The outcome of interest was defined as sputum culture conversion within 3 months, and we analyzed the association between BMI and this outcome.

resultsAmong the 218 patients, 53 patients (24.3%) had a low BMI (<18.5 kg/m²). In the multivariate Cox proportional-hazards regression analysis, failure to achieve sputum culture conversion within 3 months was independently associated with having a low BMI (hazard ratio [HR]: 1.741, 95% confidence interval [CI]: 1.006-3.013; P = 0.047) and a positive sputum smear at the initiation of therapy (HR: 8.440, 95% CI: 1.146-62.138, P = 0.036).

conclusionLow BMI (<18.5 kg/m²) was an independent risk factor for failure to achieve sputum culture conversion within 3 months among patients with MDR-TB.

Indexed as

Multidrug-resistantNutritional statusRisk factorsSputumTuberculosis

Identifiers

PMID27883374
PMCPMC5204011
OpenAlexW2552817597

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.