ArticleScientific reports2016
Telomeres are elongated in older individuals in a hibernating rodent, the edible dormouse (Glis glis).
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 78 citations in OpenAlex.
- Food deprivation is associated with telomere elongation during hibernation in a primate.Biology letters · 2025Article
- Impact of trainability on telomere dynamics of pet dogs (Canis lupus familiaris): An explorative study in aging dogs.PloS one · 2025Article
- Immune response accelerated telomere shortening during early life stage of a passerine bird, the blue tit (Biology letters · 2025Article
- Telomere dynamics during hibernation in a tropical primate.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024Article
- Sex and early-life conditions shape telomere dynamics in an ectotherm.The Journal of experimental biology · 2024Article
- Hibernation telomere dynamics in a shifting climate: insights from wild greater horseshoe bats.Proceedings. Biological sciences · 2023Article
- Food availability positively affects the survival and somatic maintenance of hibernating garden dormice (Eliomys quercinus).Frontiers in zoology · 2023Article
- Temperature-independent telomere lengthening with age in the long-lived human fish (Proceedings. Biological sciences · 2023Article
- Longitudinal telomere dynamics within natural lifespans of a wild bird.Scientific reports · 2023Article
- Seasonal variation in telomerase activity and telomere dynamics in a hibernating rodent, the garden dormouse (Frontiers in physiology · 2023Article
- Why hibernate? Predator avoidance in the edible dormouse.Mammal research · 2023Review
- Large mammal telomere length variation across ecoregions.BMC ecology and evolution · 2022Article
- Telomere dynamics in female Columbian ground squirrels: recovery after emergence and loss after reproduction.Oecologia · 2022Article
- Hibernation slows epigenetic ageing in yellow-bellied marmots.Nature ecology & evolution · 2022Article
- Evidence of Paternal Effects on Telomere Length Increases in Early Life.Frontiers in genetics · 2022Article
- Seasonal variation in telomere dynamics in African striped mice.Oecologia · 2020Article
- Telomere attrition with age in a wild amphibian population.Biology letters · 2020Article
- Physiological, Behavioral, and Life-History Adaptations to Environmental Fluctuations in the Edible Dormouse.Frontiers in physiology · 2020Review
- Article
- Always a price to pay: hibernation at low temperatures comes with a trade-off between energy savings and telomere damage.Biology letters · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Telomere shortening is thought to be an important biomarker for life history traits such as lifespan and aging, and can be indicative of genome integrity, survival probability and the risk of cancer development. In humans and other animals, telomeres almost always shorten with age, with more rapid telomere attrition in short-lived species. Here, we show that in the edible dormouse (Glis glis) telomere length significantly increases from an age of 6 to an age of 9 years. While this finding could be due to higher survival of individuals with longer telomeres, we also found, using longitudinal measurements, a positive effect of age on the rate of telomere elongation within older individuals. To our knowledge, no previous study has reported such an effect of age on telomere lengthening. We attribute this exceptional pattern to the peculiar life-history of this species, which skips reproduction in years with low food availability. Further, we show that this "sit tight" strategy in the timing of reproduction is associated with an increasing likelihood for an individual to reproduce as it ages. As reproduction could facilitate telomere attrition, this life-history strategy may have led to the evolution of increased somatic maintenance and telomere elongation with increasing age.
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