Evidence map›Paper›PMID 27883025›Full record

ArticleScientific reports2016

MathIOmica: An Integrative Platform for Dynamic Omics.

George I Mias, Tahir Yusufaly, Raeuf Roushangar, Lavida R K Brooks, Vikas V Singh, Christina Christou

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

George I MiasMichigan State University, Biochemistry and Molecular Biology, East Lansing, MI 48824, USA.
Tahir YusufalyUniversity of Southern California, Department of Physics and Astronomy, Los Angeles, CA, 90089, USA.
Raeuf RoushangarMichigan State University, Biochemistry and Molecular Biology, East Lansing, MI 48824, USA.
Lavida R K BrooksMichigan State University, Biochemistry and Molecular Biology, East Lansing, MI 48824, USA.
Vikas V SinghMichigan State University, Biochemistry and Molecular Biology, East Lansing, MI 48824, USA.
Christina ChristouMercy Cancer Center, Department of Radiation Oncology, Mason City, IA 50401, USA.

Funding

Integrative Dynamic Omics Profiling: A First Step Towards Personalized MedicineR00HG007065 · NHGRI · MICHIGAN STATE UNIVERSITY · PI MIAS, GEORGE IOANNOU · 2014 to 2016
$745k
Integrative Dynamic Omics Profiling: A First Step Towards Personalized MedicineK99HG007065 · NHGRI · STANFORD UNIVERSITY · PI MIAS, GEORGE IOANNOU · 2013 to 2013
$90k
NHGRI NIH HHS K99 HG007065NHGRI NIH HHS R00 HG007065
6 · The paper itself

Abstract

Multiple omics data are rapidly becoming available, necessitating the use of new methods to integrate different technologies and interpret the results arising from multimodal assaying. The MathIOmica package for Mathematica provides one of the first extensive introductions to the use of the Wolfram Language to tackle such problems in bioinformatics. The package particularly addresses the necessity to integrate multiple omics information arising from dynamic profiling in a personalized medicine approach. It provides multiple tools to facilitate bioinformatics analysis, including importing data, annotating datasets, tracking missing values, normalizing data, clustering and visualizing the classification of data, carrying out annotation and enumeration of ontology memberships and pathway analysis. We anticipate MathIOmica to not only help in the creation of new bioinformatics tools, but also in promoting interdisciplinary investigations, particularly from researchers in mathematical, physical science and engineering fields transitioning into genomics, bioinformatics and omics data integration.

Indexed as

SoftwareComputational BiologyGene OntologyHumansMolecular Sequence AnnotationProteomics

Identifiers

PMID27883025
PMCPMC5121649

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.