ArticleScientific reports2016
Bumble bee parasite strains vary in resistance to phytochemicals.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Can floral nectars reduce transmission of Leishmania?PLoS neglected tropical diseases · 2022Pooled it
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- Roles of Mitochondrial Fusion and Division in Harmine Derivative H-2-168-Induced Neurotoxicity.Journal of immunology research · 2025Article
- PhytochemicalOpen biology · 2024Article
- Honeybee visitation to shared flowers increasesEcology and evolution · 2023Article
- Analysis of the microbial diversity in takin (Frontiers in microbiology · 2023Article
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- Host and gut microbiome modulate the antiparasitic activity of nectar metabolites in a bumblebee pollinator.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Complex networks of parasites and pollinators: moving towards a healthy balance.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Understanding effects of floral products on bee parasites: Mechanisms, synergism, and ecological complexity.International journal for parasitology. Parasites and wildlife · 2022Article
- Chemical Stimulants and Stressors Impact the Outcome of Virus Infection and Immune Gene Expression in Honey Bees (Frontiers in immunology · 2021Article
- Antiparasitic potential of Nephrolepis biserrata methanol extract against the parasitic leech Zeylanicobdella arugamensis (Hirudinea) and LC-QTOF analysis.Scientific reports · 2020Article
- Article
- Cross-infectivity of honey and bumble bee-associated parasites across three bee families.Parasitology · 2020Article
- Herbivory and Time Since Flowering Shape Floral Rewards and Pollinator-Pathogen Interactions.Journal of chemical ecology · 2020Article
- Young bumblebees may rely on both direct pollen cues and early experience when foraging.Proceedings. Biological sciences · 2020Article
- Flowering plant composition shapes pathogen infection intensity and reproduction in bumble bee colonies.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Temperature dependence of parasitic infection and gut bacterial communities in bumble bees.Environmental microbiology · 2019Article
- Chemical Fingerprint of 'Oblačinska' Sour Cherry (Biomolecules · 2019Article
- Bee pathogen transmission dynamics: deposition, persistence and acquisition on flowers.Proceedings. Biological sciences · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nectar and pollen contain diverse phytochemicals that can reduce disease in pollinators. However, prior studies showed variable effects of nectar chemicals on infection, which could reflect variable phytochemical resistance among parasite strains. Inter-strain variation in resistance could influence evolutionary interactions between plants, pollinators, and pollinator disease, but testing direct effects of phytochemicals on parasites requires elimination of variation between bees. Using cell cultures of the bumble bee parasite Crithidia bombi, we determined (1) growth-inhibiting effects of nine floral phytochemicals and (2) variation in phytochemical resistance among four parasite strains. C. bombi growth was unaffected by naturally occurring concentrations of the known antitrypanosomal phenolics gallic acid, caffeic acid, and chlorogenic acid. However, C. bombi growth was inhibited by anabasine, eugenol, and thymol. Strains varied >3-fold in phytochemical resistance, suggesting that selection for phytochemical resistance could drive parasite evolution. Inhibitory concentrations of thymol (4.53-22.2 ppm) were similar to concentrations in Thymus vulgaris nectar (mean 5.2 ppm). Exposure of C. bombi to naturally occurring levels of phytochemicals-either within bees or during parasite transmission via flowers-could influence infection in nature. Flowers that produce antiparasitic phytochemicals, including thymol, could potentially reduce infection in Bombus populations, thereby counteracting a possible contributor to pollinator decline.
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