ArticleNature communications2016
Global gain modulation generates time-dependent urgency during perceptual choice in humans.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
- Beta-Blocker Propranolol Modulates Decision Urgency During Sequential Information Gathering.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Trial
- Transcutaneous vagus nerve stimulation boosts evidence accumulation during perceptual decision making.iScience · 2026Article
- Regulation of the decision threshold by the locus coeruleus.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- A Movement-Independent Signature of Urgency during Human Perceptual Decision-Making.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Phasic and tonic arousal distinctly shape human decision bias.Communications biology · 2026Article
- Misspecified models create the appearance of adaptive control during value-based choice.Communications psychology · 2026Article
- Pupillary dynamics during hands-off L2 driving and transitions of control under high cognitive load.PloS one · 2026Article
- Error Cancellation During Early Task Performance.Experimental psychology · 2025Article
- Phasic Alertness Impairs Cognitive Control by Amplifying Competition between Evidence Accumulators.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Parameter estimation of hyper-spherical diffusion models with a time-dependent threshold: An integral equation method.Behavior research methods · 2025Article
- Joint models reveal human subcortical underpinnings of choice and learning behavior.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Time-adaptive modulation of evidence evaluation in rat posterior parietal cortex.bioRxiv : the preprint server for biology · 2025Article
- A solvable neural circuit model revealing the dynamical principle of non-optimal temporal weighting in perceptual decision making.Journal of computational neuroscience · 2025Article
- Article
- Disentangling sources of variability in decision-making.Nature reviews. Neuroscience · 2025Review
- Subcortical nuclei of the human ascending arousal system encode anticipated reward but do not predict subsequent memory.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Neural mechanisms of metacognitive improvement under speed pressure.Communications biology · 2025Article
- Article
- Pupillary responses to directional uncertainty while intercepting a moving target.Royal Society open science · 2024Article
- The gated cascade diffusion model: An integrated theory of decision making, motor preparation, and motor execution.Psychological review · 2024Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Decision-makers must often balance the desire to accumulate information with the costs of protracted deliberation. Optimal, reward-maximizing decision-making can require dynamic adjustment of this speed/accuracy trade-off over the course of a single decision. However, it is unclear whether humans are capable of such time-dependent adjustments. Here, we identify several signatures of time-dependency in human perceptual decision-making and highlight their possible neural source. Behavioural and model-based analyses reveal that subjects respond to deadline-induced speed pressure by lowering their criterion on accumulated perceptual evidence as the deadline approaches. In the brain, this effect is reflected in evidence-independent urgency that pushes decision-related motor preparation signals closer to a fixed threshold. Moreover, we show that global modulation of neural gain, as indexed by task-related fluctuations in pupil diameter, is a plausible biophysical mechanism for the generation of this urgency. These findings establish context-sensitive time-dependency as a critical feature of human decision-making.
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