Evidence map›Paper›PMID 27882485›Full record

ArticleInternational journal of hematology2017

Pharmacodynamics of T cell function for monitoring pharmacologic immunosuppression after allogeneic hematopoietic stem cell transplantation.

Carmen Martínez, Olga Millán, Montserrat Rovira, Francesc Fernández-Avilés, Anna López, María Suárez-Lledó, Enric Carreras, Álvaro Urbano-Ispízua, Mercè Brunet

Abstract read
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In one paragraph

Article in International journal of hematology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Carmen MartínezHematology Department, Institute of Hematology and Oncology, Hospital Clínic, University of Barcelona, Villarroel 170, 08039, Barcelona, Spain. cmarti@clinic.ub.es.
Olga MillánPharmacology and Toxicology Department, Biomedical Diagnostic Center, Hospital Clínic, University of Barcelona, Barcelona, Spain.
Montserrat RoviraHematology Department, Institute of Hematology and Oncology, Hospital Clínic, University of Barcelona, Villarroel 170, 08039, Barcelona, Spain.
Francesc Fernández-AvilésHematology Department, Institute of Hematology and Oncology, Hospital Clínic, University of Barcelona, Villarroel 170, 08039, Barcelona, Spain.
Anna LópezPharmacology and Toxicology Department, Biomedical Diagnostic Center, Hospital Clínic, University of Barcelona, Barcelona, Spain.
María Suárez-LledóHematology Department, Institute of Hematology and Oncology, Hospital Clínic, University of Barcelona, Villarroel 170, 08039, Barcelona, Spain.
Enric CarrerasInstitut Josep Carreras, Hospital Clínic, University of Barcelona, Barcelona, Spain.
Álvaro Urbano-IspízuaHematology Department, Institute of Hematology and Oncology, Hospital Clínic, University of Barcelona, Villarroel 170, 08039, Barcelona, Spain.
Mercè BrunetPharmacology and Toxicology Department, Biomedical Diagnostic Center, Hospital Clínic, University of Barcelona, Barcelona, Spain.
Universitat de Barcelona · ESJosep Carreras Leukaemia Research Institute · ESCentro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Information on pharmacodynamic monitoring after allogeneic hematopoietic cell transplantation (allo-SCT) to evaluate individual responses to immunosuppressive drugs is scarce. We studied the relationship between a panel of pharmacodynamic markers monitored during the first 3 months after transplant and the occurrence of graft-versus-host disease (GVHD). Lymphocyte activation assessed by intracellular ATP concentration in CD4

Indexed as

AdultAgedAllograftsBiomarkersCD4-CD8 RatioDrug MonitoringFemaleGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansImmunosuppression TherapyImmunosuppressive AgentsLymphocyte ActivationMaleMiddle AgedPilot ProjectsBiomarkersImmunosuppressive AgentsAllogeneic stem cell transplantationGraft-versus-host diseasePharmacodynamicsT effector cellsTreg cells

Identifiers

PMID27882485
OpenAlexW2555610936

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.