Evidence map›Paper›PMID 27882441›Full record

ArticleMolecular and cellular biochemistry2017

Regioselective synthesis and biological studies of novel 1-aryl-3, 5-bis (het) aryl pyrazole derivatives as potential antiproliferative agents.

Hanumappa Ananda, Kothanahally S Sharath Kumar, Mayilaadumveettil Nishana, Mahesh Hegde, Mrinal Srivastava, Raghava Byregowda, Bibha Choudhary, Sathees C Raghavan, Kanchugarakoppal S Rangappa

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Article in Molecular and cellular biochemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Hanumappa AnandaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru, 570006, India.
Kothanahally S Sharath KumarDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru, 570006, India.
Mayilaadumveettil NishanaDepartment of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Mahesh HegdeDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru, 570006, India.
Mrinal SrivastavaDepartment of Biochemistry, Indian Institute of Science, Bangalore, 560012, India.
Raghava ByregowdaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru, 570006, India.
Bibha ChoudharyInstitute of Bioinformatics and Applied Biotechnology, Electronics City, Bangalore, 560 100, India.
Sathees C RaghavanDepartment of Biochemistry, Indian Institute of Science, Bangalore, 560012, India. sathees@biochem.iisc.ernet.in.
Kanchugarakoppal S RangappaDepartment of Studies in Chemistry, University of Mysore, Manasagangotri, Mysuru, 570006, India. rangappaks@chemistry.uni-mysore.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrazole moiety represents an important category of heterocyclic compound in pharmaceutical and medicinal chemistry. The novel 1-aryl-3, 5-bis (het) aryl pyrazole derivatives were synthesized with complementary regioselectivity. The chemical structures were confirmed by IR,

Indexed as

Antineoplastic AgentsCytotoxinsPyrazolesAnimalsBreast NeoplasmsCell DeathCell ProliferationFemaleHumansK562 CellsLeukemiaMass SpectrometryMCF-7 CellsMiceAntineoplastic AgentsCytotoxinsPyrazolesApoptosisBreast cancerDithioestersMCF7PyrazoleRegioselectivity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.