Evidence map›Paper›PMID 27882343›Full record

ArticleJCI insight2016

Proapoptotic protein Bim attenuates estrogen-enhanced survival in lymphangioleiomyomatosis.

Chenggang Li, Na Li, Xiaolei Liu, Erik Y Zhang, Yang Sun, Kouhei Masuda, Jing Li, Julia Sun, Tasha Morrison, Xiangke Li and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JCI insight, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis.bioRxiv : the preprint server for biology · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models.American journal of respiratory cell and molecular biology · 2018
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Chenggang LiUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Na LiUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Xiaolei LiuUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Erik Y ZhangUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Yang SunUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Kouhei MasudaUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Jing LiHarvard Medical School, Department of Cell Biology, Boston, Massachusetts, USA.
Julia SunUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Tasha MorrisonBoston University School of Medicine, Department Molecular and Translational Medicine, Boston, Massachusetts, USA.
Xiangke LiUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Yuanguang ChenUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Jiang WangUniversity of Cincinnati College of Medicine, Department of Pathology and Lab Medicine, Cincinnati, OH, USA.
Nagla A KarimUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Division of Hematology and Oncology, Cincinnati, Ohio, USA.
Yi ZhangThe First Affiliated Hospital of Zhengzhou University, Biotherapy Center and Department of Oncology, Zhengzhou, Henan, China.
John BlenisHarvard Medical School, Department of Cell Biology, Boston, Massachusetts, USA.
Mauricio J ReginatoDrexel University College of Medicine, Department of Biochemistry and Molecular Biology, Philadelphia, Pennsylvania, USA.
Elizabeth P HenskeBrigham and Women's Hospital-Harvard Medical School, Boston, Massachusetts, USA.
Jane J YuUniversity of Cincinnati College of Medicine, Department of Internal Medicine, Pulmonary, Critical Care and Sleep Medicine, Cincinnati, Ohio, USA.
Drexel University · US

Funding

Targeting the Estrogen Pathway for the Prevention and Treatment of LAMR01HL098216 · NHLBI · UNIVERSITY OF CINCINNATI · PI YU, JANE · 2010 to 2014
$2.1M
Prostaglandin biosynthesis: a novel therapeutic target in TSC disordersR01DK098331 · NIDDK · UNIVERSITY OF CINCINNATI · PI YU, JANE · 2014 to 2016
$739k
NHLBI NIH HHS R01 HL098216NIDDK NIH HHS R01 DK098331
6 · The paper itself

Abstract

Lymphangioleiomyomatosis (LAM) is a progressive lung disease that primarily affects young women. Genetic evidence suggests that LAM cells bearing

Indexed as

AnoikisAnimalsBcl-2-Like Protein 11BortezomibEstrogensFemaleHumansLungLung DiseasesLymphangioleiomyomatosisMiceMice, SCIDTuberous Sclerosis Complex 2 ProteinTumor Cells, CulturedTumor Suppressor ProteinsBcl-2-Like Protein 11BortezomibEstrogensTSC2 protein, humanTsc2 protein, mouseTuberous Sclerosis Complex 2 ProteinTumor Suppressor Proteins

Identifiers

PMID27882343
PMCPMC5111508
OpenAlexW2550489497

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.