Evidence map›Paper›PMID 27882213›Full record

ArticleBiomedical reports2016

Endometriosis research using capture microdissection techniques: Progress and future applications.

Luyang Zhao, Chenglei Gu, Ke Huang, Weidong Han, Meng Fu, Yuanguang Meng

Open access · bronzeAbstract read
In one paragraph

Article in Biomedical reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luyang ZhaoDepartment of Gynecology and Obstetrics, Chinese People's Liberation Army (PLA) Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Chenglei GuDepartment of Gynecology and Obstetrics, Chinese People's Liberation Army (PLA) Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China; Department of Gynecology and Obstetrics, the 309th Hospital of the PLA, Beijing 100091, P.R. China.
Ke HuangDepartment of Gynecology and Obstetrics, Chinese People's Liberation Army (PLA) Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Weidong HanDepartment of Molecular Biology, Institute of Basic Medicine, PLA Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Meng FuDepartment of Gynecology and Obstetrics, Chinese People's Liberation Army (PLA) Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China; Department of Gynecology and Obstetrics, Haidian Maternal and Child Health Hospital, Beijing 100080, P.R. China.
Yuanguang MengDepartment of Gynecology and Obstetrics, Chinese People's Liberation Army (PLA) Medical School, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Chinese PLA General Hospital · CNChinese People's Liberation Army · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a common gynecological disease with high prevalence, while its etiology and pathophysiology have remained to be fully elucidated. Previous evidence suggested that this disorder may be in part or completely of somatic origin. However, traditional endometrial samples may not be ideal for investigation, as target cells, including epithelial and stromal cells, in endometriotic lesions are too sparse to be analyzed. Recently, capture microdissection techniques have been used to overcome these limitations and eliminate tissue heterogeneity in endometriosis research. Therefore, the present review summarized the alterations in epithelial and stromal cells in endometriosis tissues isolated through capture microdissection, outlined recent progress and provided directions for future investigation of the pathogenesis of endometriosis.

Indexed as

clonality analysisendometriosisloss of heterozygositymicrodissectionsomatic copy number alteration

Identifiers

PMID27882213
PMCPMC5103660
OpenAlexW2519799571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.