ArticleTransactions of the American Ophthalmological Society2016
Tank-Binding Kinase 1 (
Open access · greenAbstract read
In one paragraph
Article in Transactions of the American Ophthalmological Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 26 citations in OpenAlex.
- Genetic Architecture and Clinical Phenotypes of Primary Open-Angle Glaucoma: An Updated Review of Mendelian Genes, GWAS Loci, and Polygenic Risk.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Inhibiting NLRP3 Inflammasome Activation to Alleviate Retinal Inflammation and Protect the Optic Nerve of OPTN(E50K)Mice.Inflammation · 2025Article
- Emerging strategies targeting genes and cells in glaucoma.Vision research · 2025Review
- Tank-binding kinase 1 regulates inflammation and autophagy in glaucoma.Frontiers in neuroscience · 2025Review
- Genetic Basis of Pigment Dispersion Syndrome and Pigmentary Glaucoma: An Update and Functional Insights.Genes · 2024Review
- Review
- Identification of hub genes for glaucoma: a study based on bioinformatics analysis and experimental verification.International journal of ophthalmology · 2023Article
- METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma.The Journal of clinical investigation · 2022Article
- The role of TBK1 in cancer pathogenesis and anticancer immunity.Journal of experimental & clinical cancer research : CR · 2022Review
- Significance of mitochondrial activity in neurogenesis and neurodegenerative diseases.Neural regeneration research · 2022Review
- Immunogenetics of the Ocular Anterior Segment: Lessons from Inherited Disorders.Journal of ophthalmology · 2021Review
- Review
- Long-Term Follow-Up of Normal Tension Glaucoma Patients With TBK1 Gene Mutations in One Large Pedigree.American journal of ophthalmology · 2020Article
- The Role of Neuroinflammation in Glaucoma: An Update on Molecular Mechanisms and New Therapeutic Options.Frontiers in neurology · 2020Review
- Mendelian genes in primary open angle glaucoma.Experimental eye research · 2019Review
- Dysfunction of Optineurin in Amyotrophic Lateral Sclerosis and Glaucoma.Frontiers in immunology · 2018Review
- Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer.Frontiers in immunology · 2018Review
- Genetics of glaucoma.Human molecular genetics · 2017Review
- Major review: Molecular genetics of primary open-angle glaucoma.Experimental eye research · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
John H FingertDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Departments of Ophthalmology and International Health, School of Medicine and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland (Dr Robin); the Department of Ophthalmology, University of Maryland, Baltimore, Maryland (Dr Robin); Columbia University Medical Center, New York, New York (Dr Liebmann); the Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York (Dr Ritch).
Alan L RobinDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Departments of Ophthalmology and International Health, School of Medicine and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland (Dr Robin); the Department of Ophthalmology, University of Maryland, Baltimore, Maryland (Dr Robin); Columbia University Medical Center, New York, New York (Dr Liebmann); the Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York (Dr Ritch).
Todd E ScheetzDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Departments of Ophthalmology and International Health, School of Medicine and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland (Dr Robin); the Department of Ophthalmology, University of Maryland, Baltimore, Maryland (Dr Robin); Columbia University Medical Center, New York, New York (Dr Liebmann); the Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York (Dr Ritch).
Young H KwonDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Departments of Ophthalmology and International Health, School of Medicine and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland (Dr Robin); the Department of Ophthalmology, University of Maryland, Baltimore, Maryland (Dr Robin); Columbia University Medical Center, New York, New York (Dr Liebmann); the Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York (Dr Ritch).
Jeffrey M LiebmannDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Departments of Ophthalmology and International Health, School of Medicine and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland (Dr Robin); the Department of Ophthalmology, University of Maryland, Baltimore, Maryland (Dr Robin); Columbia University Medical Center, New York, New York (Dr Liebmann); the Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York (Dr Ritch).
Robert RitchDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Departments of Ophthalmology and International Health, School of Medicine and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland (Dr Robin); the Department of Ophthalmology, University of Maryland, Baltimore, Maryland (Dr Robin); Columbia University Medical Center, New York, New York (Dr Liebmann); the Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York (Dr Ritch).
Wallace L M AlwardDepartment of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Stephen A. Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa (Dr Fingert, Dr Scheetz, Dr Kwon, Dr Alward); the Departments of Ophthalmology and International Health, School of Medicine and the Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland (Dr Robin); the Department of Ophthalmology, University of Maryland, Baltimore, Maryland (Dr Robin); Columbia University Medical Center, New York, New York (Dr Liebmann); the Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York (Dr Ritch).
University of Iowa · USColumbia University Irving Medical Center · US
Funding
Molecular Genetics of Norma Tension GlaucomaR01EY023512 · NEI · UNIVERSITY OF IOWA · PI FINGERT, JOHN H, MULLINS, ROBERT FOSTER · 2014 to 2017
$1.8MNEI NIH HHS R01 EY023512
Abstract
purposeTo investigate the role of TANK-binding kinase 1 (
methodsIn previous studies, we discovered that copy-number variations in the
resultsNo
conclusions
Indexed as
MutationAgedCase-Control StudiesDNADNA Mutational AnalysisFemaleFollow-Up StudiesGene DosageGlaucoma, Open-AngleHumansMaleOphthalmologyProspective StudiesProtein Serine-Threonine KinasesSocieties, MedicalUnited StatesDNAProtein Serine-Threonine KinasesTBK1 protein, human
Identifiers
PMID
27881886PMC
PMC5113957OpenAlex
W2558129454What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.