Evidence map›Paper›PMID 27881873›Full record

ArticleLeukemia2017

Induction of iron excess restricts malignant plasma cells expansion and potentiates bortezomib effect in models of multiple myeloma.

J Bordini, S Galvan, M Ponzoni, M T S Bertilaccio, M Chesi, P L Bergsagel, C Camaschella, A Campanella

Abstract read
PubMed Publisher
In one paragraph

Article in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Research Progress on Ferroptosis in Multiple Myeloma.Current treatment options in oncology · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. The Role of Iron in Benign and Malignant Hematopoiesis.Antioxidants & redox signaling · 2021
    Review
  15. Article
  16. Review
  17. The iron chelator deferoxamine decreases myeloma cell survival.The Journal of international medical research · 2021
    Article
  18. Article
  19. Review
  20. The Multifaceted Role of Heme in Cancer.Frontiers in oncology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

J BordiniDivision of Genetics and Cell Biology, IRCCS Ospedale San Raffaele,Milan, Italy.
S GalvanDivision of Genetics and Cell Biology, IRCCS Ospedale San Raffaele,Milan, Italy.
M PonzoniPathology and Myeloma Units, IRCCS Ospedale San Raffaele, Milan, Italy.
M T S BertilaccioDivision of Molecular Oncology, IRCCS Ospedale San Raffaele, Milan, Italy.
M ChesiComprehensive Cancer Center, Mayo Clinic, Scottsdale, AZ, USA.
P L BergsagelComprehensive Cancer Center, Mayo Clinic, Scottsdale, AZ, USA.
C CamaschellaDivision of Genetics and Cell Biology, IRCCS Ospedale San Raffaele,Milan, Italy.
A CampanellaDivision of Genetics and Cell Biology, IRCCS Ospedale San Raffaele,Milan, Italy.

Funding

Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Rafael Fonseca · 2015 to 2026
$25.5M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBortezomibCell DeathCell Line, TumorCell ProliferationDisease ProgressionHumansIronMiceMultiple MyelomaPlasma CellsBortezomibIron

Identifiers

PMID27881873

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.