ArticleHypertension research : official journal of the Japanese Society of Hypertension2017
Expression and methylation of circulating microRNA-510 in essential hypertension.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Accelerated epigenetic age in hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Pooled it
- Blood-Based DNA Methylation Biomarkers to Identify Risk and Progression of Cardiovascular Disease.International journal of molecular sciences · 2025Review
- Peripheral whole blood microRNA expression in relation to vascular function: a population-based study.Journal of translational medicine · 2024Article
- Article
- The relationship between serum miR-21 levels and left atrium dilation in elderly patients with essential hypertension.Journal of geriatric cardiology : JGC · 2022Article
- MiR-3571 modulates the proliferation and migration of vascular smooth muscle cells by targeting claudin 1.International journal of medical sciences · 2022Article
- Impact of Nutritional Epigenetics in Essential Hypertension: Targeting microRNAs in the Gut-Liver Axis.Current hypertension reports · 2021Review
- Exosomal MicroRNAs Contribute to Cognitive Impairment in Hypertensive Patients by Decreasing Frontal Cerebrovascular Reactivity.Frontiers in neuroscience · 2021Article
- Decoding the functional role of long noncoding RNAs (lncRNAs) in hypertension progression.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Circular RNAs in hypertension: challenges and clinical promise.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Review
- Circular RNA: a new biomarker for different types of hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Methylation-dependent circulating microRNA 510 in preeclampsia patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Noncoding RNAs in Hypertension.Hypertension (Dallas, Tex. : 1979) · 2019Review
- Epigenetic modification: a regulatory mechanism in essential hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Review
- Epigenetic Biomarkers in Cardiovascular Diseases.Frontiers in genetics · 2019Review
- Decreased expression of microRNA-510 in intestinal tissue contributes to post-infectious irritable bowel syndrome via targeting PRDX1.American journal of translational research · 2019Article
- Noncoding RNAs in the Regulatory Network of Hypertension.Hypertension (Dallas, Tex. : 1979) · 2018Review
- The regulatory role of microRNAs in angiogenesis-related diseases.Journal of cellular and molecular medicine · 2018Review
- Comment on the potential role of microRNAs in hypertension.Journal of human hypertension · 2018Article
- microRNA-21 and hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension (HTN) is one of the most common emerging disease in developing countries. It alters endothelial cell structure and function, resulting in several diseases, such as cardiovascular disease, peripheral vasculopathy, cerebrovascular disease and nephropathy. Although much progress has been made in researching HTN in recent years, early diagnosis and treatment of HTN are not yet satisfactory, and progression control/treatment is still poor. MicroRNAs are well-known regulators of the physiological and developmental processes of HTN. Our results revealed that miR-510 was upregulated in blood samples from HTN patients, whereas no significant differences were observed in the control samples. Methylation analyses corroborated the miR-510 upregulation in patient samples. These results suggested that miR-510 can be used as a novel biomarker for diagnosis and as a new therapeutic target for HTN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.