ArticleOpen biology2016
Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions.
Article in Open biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Self-reactivity of CD8 T-cell clones determines their differentiation status rather than their responsiveness in infections.Frontiers in immunology · 2022Article
- Dynamics of the Coreceptor-LCK Interactions during T Cell Development Shape the Self-Reactivity of Peripheral CD4 and CD8 T Cells.Cell reports · 2020Article
- Development of an 8-color antibody panel for functional phenotyping of human CD8+ cytotoxic T cells from peripheral blood mononuclear cells.Cytotechnology · 2018Article
- T Cell Receptor-Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103Frontiers in immunology · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
T-cell identity is established by the expression of a clonotypic T-cell receptor (TCR), generated by somatic rearrangement of TCRα and β genes. The properties of the TCR determine both the degree of self-reactivity and the repertoire of antigens that can be recognized. For CD8 T cells, the relationship between TCR identity-hence reactivity to self-and effector function(s) remains to be fully understood and has rarely been explored outside of the H-2
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Registered trials
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